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galactosone
Also Known As:
2-ketoglactose; D-lyxo-2-hexosulose
Networked:
2
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Carbohydrates: 22023
Sugars: 11126
Monosaccharides: 889
Hexoses: 549
Galactose: 3212
galactosone: 2
Related Diseases
1.
Hepatocellular Carcinoma (Hepatoma)
07/15/1982 - "
d-Galactosone (d-lyxo-2-hexosulose) is phosphorylated and metabolized to the uridine diphosphate derivative in AS-30D hepatoma cells and rat liver.
"
07/15/1982 - "
Combined treatment of hepatoma cells with d-galactosone and N-(phosphonoacetyl)-l-aspartate, an inhibitor of aspartate carbamoyltransferase, prevented the expansion of the uridylate pool and led to a synergistic reduction of UTP to 10% of the content in control cells.
"
07/15/1982 - "
[(14)C]Uridine labelling of hepatoma cells indicated a division of [(14)C]uridylate from UTP into UDP-galactosone; the latter was formed at a rate of more than 1.7mmolxh(-1)x(kg AS-30D or liver wet wt.)(-1).
"
2.
Ehrlich Tumor Carcinoma
01/01/1984 - "
A comparative study on proliferation, macromolecular synthesis and energy metabolism of in vitro-grown Ehrlich ascites tumor cells in the presence of glucosone, galactosone and methylglyoxal.
"
01/01/1984 - "
Proliferation of in vitro grown Ehrlich ascites tumor cells is completely inhibited by 0.2-0.4 mM methylglyoxal and 1-2 mM glucosone or galactosone without severely affecting viability (dye exclusion test); no phase-specific arrest of cell growth is observed.
"
Related Drugs and Biologics
1.
Uridine Triphosphate (UTP)
2.
Uridine Diphosphate (UDP)
3.
Uridine
4.
Pyruvaldehyde (Methylglyoxal)
5.
Coloring Agents (Dyes)
6.
Aspartate Carbamoyltransferase
7.
glucosone
8.
sparfosic acid (PALA)