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ciamexon

Also Known As:

2-cyan-1-((2-methoxy-6-methylpyridin-3-yl)methyl)aziridine; BM 41332; BM-41332; ciamexone; 2-Aziridinecarbonitrile, 1-((2-methoxy-6-methyl-3-pyridinyl)methyl)-

Networked: 10 relevant articles (1 outcomes, 4 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azirines
    - Aziridines: 14
      - ciamexon: 10

Experts

1.	Dorr, R T: 1 article (01/2012)
2.	Remers, W A: 1 article (01/2012)

Related Diseases

1.	Rheumatoid Arthritis 05/01/1990 - "A randomized controlled trial of ciamexon versus placebo in the immunomodulatory treatment of rheumatoid arthritis." 12/09/1989 - "[Immunomodulating basic therapy of rheumatoid arthritis using ciamexone]." 12/15/1986 - "Due to its remarkably good tolerance, Ciamexone has been used in first pilot trials in different human autoimmune situations such as rheumatoid arthritis and insulin dependent diabetes mellitus.(ABSTRACT TRUNCATED AT 250 WORDS)" 05/01/1990 - "To determine the efficacy of the new immunosuppressive agent ciamexon in patients with rheumatoid arthritis (RA), we conducted a 6-month, prospective, double-blind, placebo-controlled study. "
2.	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 05/01/1989 - "The fact that Ciamexone suppresses anti-islet ADCC may explain its possible effectiveness in Type 1 diabetes." 12/15/1986 - "Due to its remarkably good tolerance, Ciamexone has been used in first pilot trials in different human autoimmune situations such as rheumatoid arthritis and insulin dependent diabetes mellitus.(ABSTRACT TRUNCATED AT 250 WORDS)" 05/01/1990 - "The data suggest that, in this animal model, ciamexone does not affect the frequency of autoimmune diabetes or lymphocytic thyroiditis nor does it affect the serum TSH or T4 concentrations." 05/01/1990 - "The effect of ciamexone on lymphocytic thyroiditis and insulin-dependent diabetes mellitus in the BB/Wor rat."
3.	Autoimmune Diseases (Autoimmune Disease) 05/01/1990 - "Previous studies have suggested that ciamexone, a 2-cyan-aziridine derivative, is a selective immunomodulatory agent with potential therapeutic application in a variety of autoimmune diseases. " 11/01/1987 - "Ciamexon is a new immuno-modulating agent with promising effects in experimental models of autoimmune diseases and practically no toxic side effects. " 12/15/1986 - "Ciamexone, a new highly selective immunomodulator, might be an interesting new approach in the treatment of autoimmune diseases. " 12/15/1986 - "Ciamexone, a highly selective immunomodulator--a tool for autoimmune diseases?"
4.	Autoimmune Thyroiditis (Lymphomatous Thyroiditis) 05/01/1990 - "In the present study, the effects of ciamexone on autoimmune lymphocytic thyroiditis and diabetes mellitus were studied in the BB rat. " 05/01/1990 - "The data suggest that, in this animal model, ciamexone does not affect the frequency of autoimmune diabetes or lymphocytic thyroiditis nor does it affect the serum TSH or T4 concentrations." 05/01/1990 - "The effect of ciamexone on lymphocytic thyroiditis and insulin-dependent diabetes mellitus in the BB/Wor rat."
5.	Neoplasms (Cancer) 01/01/2012 - "Two of these compounds, azimexon and ciamexon, showed activity against tumors in clinical trials. "

Related Drugs and Biologics

1.	Immunosuppressive Agents (Immunosuppressants)
2.	azimexon
3.	Cyclosporine (Ciclosporin)
4.	Streptozocin (Streptozotocin)
5.	Immunologic Factors (Immunomodulators)
6.	Hemoglobins (Hemoglobin)

Related Therapies and Procedures

1.	Therapeutics