3(17)-hydroxysteroid dehydrogenase

from cytosol of female rabbit kidney; acts on both androgen & estrogen substrates; this is specific for alpha-hydroxysteroids, for beta-hydroxy steroids see EC 1.1.1.51

Also Known As:

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Mani, Sugumar: 1 article (01/2020)
2.	Meenaloshani, G: 1 article (01/2020)
3.	Sali, Veeresh Kumar: 1 article (01/2020)
4.	Vasanthi, Hannah R: 1 article (01/2020)
5.	Velmurugan Ilavarasi, Anbumani: 1 article (01/2020)
6.	Lages, Luiza: 1 article (08/2012)
7.	Maier, Polyana S: 1 article (08/2012)
8.	Mattiello, Simone S: 1 article (08/2012)
9.	Spritzer, Poli M: 1 article (08/2012)
10.	Adonakis, George: 1 article (08/2009)

Related Diseases

1.	Polycystic Ovary Syndrome (Syndrome, Stein-Leventhal) 08/01/2009 - "Association of the 17-hydroxysteroid dehydrogenase type 5 gene polymorphism (-71A/G HSD17B5 SNP) with hyperandrogenemia in polycystic ovary syndrome (PCOS)." 08/01/2012 - "We studied (1) the effects of oral contraceptive pills (OCPs) on hirsutism, hormonal and metabolic variables in 49 polycystic ovary syndrome patients without metabolic comorbidities and (2) the effect of 17-hydroxysteroid dehydrogenase type 5 gene polymorphism (-71A/G HSD17B5 SNP) on the response to OCP treatment. "
2.	Breast Neoplasms (Breast Cancer) 01/01/2020 - "Type 5 17-hydroxysteroid dehydrogenase/prostaglandin F synthase (AKR1C3) inhibition and potential anti-proliferative activity of cholest-4-ene-3,6-dione in MCF-7 breast cancer cells." 01/01/1990 - "It is concluded that estrogen sulfates can play an important role in the biologic response of estrogens in breast cancer and that control of sulfatase and 17-hydroxysteroid dehydrogenase activities are key steps in the concentration and ability of estradiol in the mammary cancer cell line."
3.	Hirsutism 08/01/2012 - "We studied (1) the effects of oral contraceptive pills (OCPs) on hirsutism, hormonal and metabolic variables in 49 polycystic ovary syndrome patients without metabolic comorbidities and (2) the effect of 17-hydroxysteroid dehydrogenase type 5 gene polymorphism (-71A/G HSD17B5 SNP) on the response to OCP treatment. "

Related Drugs and Biologics

1.	Sulfates (Sulfates, Inorganic)
2.	Sulfatases
3.	Estrogens (Estrogen)
4.	Estradiol (Delestrogen)
5.	Oral Contraceptives
6.	prostaglandin-F synthase