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amyloid A-degrading serine protease
reduced in amyloidosis associated with rheumatoid arthritis
Also Known As:
AAD-protease; amyloid A-degrading activity
Networked:
6
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Enzymes and Coenzymes: 1
Enzymes: 152586
Hydrolases: 2166
Peptide Hydrolases: 23957
Serine Proteases: 3726
Serine Endopeptidases: 11
amyloid A-degrading serine protease: 6
Endopeptidases: 633
Serine Endopeptidases: 11
amyloid A-degrading serine protease: 6
Related Diseases
1.
Amyloidosis
07/31/1982 - "
Mechanism of reduced amyloid-A-degrading activity in serum of patients with secondary amyloidosis.
"
02/27/1982 - "
Reduced amyloid-A-degrading activity in serum in amyloidosis associated with rheumatoid arthritis.
"
11/01/1984 - "
Serum esterase activity in reactive systemic amyloidosis and its relation to amyloid A degrading activity.
"
04/01/1983 - "
4. We conclude that the difference in the amyloid A-degrading activity between RA patients with or without amyloidosis cannot be accounted for by differences in concentration, activity or Pi type of alpha 1-antitrypsin.
"
11/01/1984 - "
A significant correlation between serum arylesterase and amyloid A degrading activity was found (patients with rheumatoid arthritis plus amyloidosis, n = 31, r = 0.51, p less than 0.01; all patients, n = 95, r = 0.34, p less than 0.001).
"
2.
Rheumatoid Arthritis
02/27/1982 - "
Reduced amyloid-A-degrading activity in serum in amyloidosis associated with rheumatoid arthritis.
"
02/01/1983 - "
The acute phase response and its relation to amyloid A degrading activity in serum of patients with rheumatoid arthritis undergoing arthroplasty.
"
02/01/1983 - "
The sequential changes in the concentration of specific serum proteins and their relation to amyloid A degrading activity were studied in ten patients with rheumatoid arthritis undergoing arthroplasty of the knee or hip.
"
11/01/1984 - "
A significant correlation between serum arylesterase and amyloid A degrading activity was found (patients with rheumatoid arthritis plus amyloidosis, n = 31, r = 0.51, p less than 0.01; all patients, n = 95, r = 0.34, p less than 0.001).
"
3.
Liver Diseases (Liver Disease)
06/30/1983 - "
The results show that liver dysfunction per se decreases amyloid A-degrading activity in serum.
"
4.
Liver Cirrhosis (Hepatic Cirrhosis)
06/30/1983 - "
The amyloid A-degrading activity was significantly decreased in liver cirrhosis.
"
5.
Acute-Phase Reaction
02/01/1983 - "
A significant fall in the amyloid A degrading activity of serum occurred during the acute phase reaction.
"
02/01/1983 - "
The acute phase response and its relation to amyloid A degrading activity in serum of patients with rheumatoid arthritis undergoing arthroplasty.
"
Related Drugs and Biologics
1.
Esterases
2.
Blood Proteins (Serum Proteins)
3.
alpha 1-Antitrypsin (alpha 1 Antitrypsin)
4.
arylesterase
Related Therapies and Procedures
1.
Arthroplasty