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(alpha-carboxycyclopropyl)glycine (CCPG)

Subscribe to New Research on (alpha-carboxycyclopropyl)glycine

structure given in first source; glutamate receptor agonist

Also Known As:

CCPG; (alpha-carboxycyclopropyl)glycine, (1R-(1alpha(S*),2alpha))-isomer; (alpha-carboxycyclopropyl)glycine, (1R-(1alpha(S*),2beta))-isomer; (alpha-carboxycyclopropyl)glycine, (1S-(1alpha(R*),2alpha))-isomer; (alpha-carboxycyclopropyl)glycine, (1S-(1alpha(R*),2beta))-isomer; 2-(carboxycyclopropyl)glycine; 3,4-cyclopropylglutamate; L-2-(carboxypropyl)glycine; L-CCG III; L-CCG-I; alpha-(carboxycyclopropyl)glycine; Cyclopropaneacetic acid, alpha-amino-2-carboxy-

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins
- Amino Acids: 10808
  - Dicarboxylic Amino Acids: 22
    - (alpha-carboxycyclopropyl)glycine: 5

Experts

1.	Steinberg, Marvin A: 1 article (01/2005)
2.	Potenza, Marc N: 1 article (01/2005)
3.	Wu, Ran: 1 article (01/2005)
4.	Dolan, S: 1 article (09/2002)
5.	Nolan, A M: 1 article (09/2002)

Related Diseases

1.	Seizures (Seizure) 02/19/1999 - "While DHPG (400 nmoles) induced EEG and behavioural limbic seizures, L-CCG-I (400 nmoles) and L-AP4 (800 nmoles) induced a 'depressant' EEG with an increase in relative power in the slow-frequency bands and a decrease in relative power in the high-frequency bands) and behavioural effects. " 03/19/1999 - "Pretreatment i.c.v. with a presynaptic mGlu receptor agonist (the group 2 mGlu receptor agonist (2S,1'S,2'S)-2-(carboxycyclopropyl)-glycine (L-CCG-I: 3.0 and 5.6 nmol) and the group 3 mGlu receptor agonist, L-amino-4-phosphonobutyric acid (L-AP4: 3.0 and 5.6 nmol)) failed to suppress the decrease in seizure threshold in diazepam-withdrawn mice, but increased the seizure threshold in control mice. "
2.	Hyperalgesia 09/01/2002 - "Intrathecal administration of the group II mGluR agonist (2S,1S,2S)-2-(carboxycyclopropyl)glycine (L-CCG-I; 620 nmol) given either before or after carrageenan treatment produced analgesia and anti-hyperalgesia, an effect abolished by co-administration of EGLU (570 nmol). "
3.	Gambling (Pathological Gambling) 01/01/2005 - "The characteristics of problem gamblers calling the Connecticut Council on Problem Gambling (CCPG) gambling helpline during the years 2000-2001 (n = 960) were examined based on the presence or absence of self-reported alcohol use problems. "
4.	Catalepsy 08/28/1998 - "The group II agonist (2S,3S,4S)-alpha-carboxycyclopropyl-glycine (L-CCG I) dose dependently induced catalepsy, infused intracerebroventricular (i.c.v.) in rats. "

Related Drugs and Biologics

1.	Glycine (Aminoacetic Acid)
2.	Diazepam (Valium)
3.	Carrageenan
4.	Carbon Monoxide
5.	dihydroxyphenylethylene glycol

Related Therapies and Procedures

1.	Analgesia