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mirtazapine (Rexer)

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Also Known As:

Rexer; Remeron; Zispin; (N-methyl-11C)mirtazapine; 6-azamianserin; Celltech brand of mirtazapine; Mundogen brand of mirtazapine; Norset; ORG 3770; ORG-3770; Organon brand of mirtazapine; Remergil; Pyrazino(2,1-a)pyrido(2,3-c)(2)benzazepine, 1,2,3,4,10,14b-hexahydro-2-methyl-

Networked: 602 relevant articles (114 outcomes, 143 trials/studies)

Relationship Network

Drug Context: Research Results

Heterocyclic Compounds: 60
- 3-Ring Heterocyclic Compounds
  - Dibenzazepines: 2
    - Mianserin: 322
      - mirtazapine: 602

Experts

1.	Lee, Min-Soo: 7 articles (05/2015 - 01/2007)
2.	Burkin, Mark: 7 articles (08/2013 - 03/2009)
3.	Stenberg, Jan-Henry: 7 articles (08/2013 - 03/2009)
4.	Joffe, Marina: 7 articles (08/2013 - 03/2009)
5.	Tiihonen, Jari: 7 articles (08/2013 - 03/2009)
6.	Joffe, Grigori: 7 articles (08/2013 - 03/2009)
7.	Pae, Chi-Un: 7 articles (02/2008 - 04/2002)
8.	Bahk, Won-Myong: 6 articles (08/2015 - 04/2002)
9.	Fava, Maurizio: 5 articles (11/2013 - 01/2002)
10.	Trivedi, Madhukar H: 5 articles (11/2013 - 07/2006)

Related Diseases

1.	Schizophrenia (Dementia Praecox) 02/01/2014 - "Our results indicate that NaSSA (especially mirtazapine) augmentation therapy improved overall and negative symptoms in patients with schizophrenia. " 04/01/2011 - "In this study, the efficacy of add-on mirtazapine on depression in schizophrenia was explored in a subsidiary arm of a recent randomized controlled trial. " 08/01/2010 - "Adjunctive mirtazapine improved negative symptoms of schizophrenia in several studies. " 04/01/2009 - "This study investigates the efficacy of adding mirtazapine to treatment as usual to alleviate the negative symptoms of schizophrenia. " 07/01/2015 - "To assess the efficacy of mirtazapine as an adjunctive treatment of negative symptoms in patients with chronic schizophrenia via meta-analysis. "
2.	Nausea 01/01/2012 - "[Low-dose mirtazapine improved nausea and appetite loss during S-1 therapy]." 01/01/2012 - "We conclude that low-dose mirtazapine is one effective option for refractory nausea duringS -1 therapy." 01/01/2012 - "Mirtazapine is a new antidepressant called noradrenergic and specific serotonergic antidepressant(NaSSA)and blocks 5-HT3 receptors to improve nausea. " 01/01/2012 - "However, refractory nausea was diagnosed because it did not improve, and mirtazapine at a daily dose of 7. 5 mgbefore bedtime was started. " 07/01/2000 - "Mirtazapine for the treatment of depression and nausea in breast and gynecological oncology."
3.	Post-Traumatic Stress Disorders (PTSD) 07/01/2009 - "Although small and with methodological limitations, this study suggests that mirtazapine is an effective treatment for combat-related PTSD. " 12/01/2005 - "These results suggest that the mirtazapine may be effective in the continuation treatment of PTSD as well as short-term treatment. " 10/01/2004 - "Mirtazapine appeared to be an effective and well-tolerated treatment for PTSD in Korean veterans." 10/01/2002 - "In this pilot study, mirtazapine was found to be effective and well tolerated in the treatment of patients with PTSD. " 01/01/1999 - "Mirtazapine was associated with clinical improvement in 50% of subjects with severe, chronic PTSD, suggesting a need for further investigation in double-blind, placebo-controlled trials."
4.	Anxiety Disorders (Anxiety Disorder) 09/01/2010 - "In conclusion, mirtazapine (30-45 mg/day) failed to be effective in the generalized social anxiety disorder." 01/01/1998 - "Mirtazapine seems to be an effective, well-tolerated antidepressant and may be effective for treating comorbid anxiety disorders." 09/01/2005 - "We investigated the efficacy of mirtazapine in the treatment of generalized anxiety disorder (GAD). " 11/01/2002 - "This open pilot study suggests that further investigations are warranted to prove the efficacy of mirtazapine in generalized social anxiety disorder." 09/01/2010 - "This study is aimed at investigating the efficacy and tolerability of mirtazapine in a generalized social anxiety disorder. "
5.	Weight Gain 06/01/2008 - "Weight gain was significantly greater on mirtazapine than on placebo in both trials. " 01/15/2011 - "The mirtazapine group exhibited a statistically significant improvement in cognitive function, including vocabulary and immediate memory, and negative symptoms (as measured by negative symptom scales) and showed an adverse effect of 5.83 kg mean weight gain. " 10/01/2001 - "Although weight gain was significantly greater in the group receiving active medication during the double-blind phase (p = .001), patients taking mirtazapine gained only 1.4 kg (3.1 lb) across the 40 weeks of continuation therapy, and there was no difference in the rates of weight gain as a newonset adverse event. " 01/01/2013 - " results from the preliminary mirtazapine study failed to be reproduced in the two more recent multicentre trials and, moreover, the use of mirtazapine was associated with significant weight gain and sleepiness. " 10/01/2014 - " conclusion, mirtazapine increased the weight gain of diabetic patients; however, other diabetic and lipid markers generally did not worsen during the 6-month treatment period. "

Related Drugs and Biologics

1.	venlafaxine (Effexor)
2.	Antidepressive Agents (Antidepressants)
3.	Serotonin (5 Hydroxytryptamine)
4.	Antipsychotic Agents (Antipsychotics)
5.	Citalopram (Escitalopram)
6.	Serotonin Uptake Inhibitors (Serotonin Reuptake Inhibitors)
7.	duloxetine (Cymbalta)
8.	nefazodone (Serzone)
9.	Fluoxetine (Prozac)
10.	Paroxetine (Paxil)

Related Therapies and Procedures

1.	Drug Therapy (Chemotherapy)
2.	Aftercare (After-Treatment)
3.	Induced Hyperthermia (Thermotherapy)
4.	Radiotherapy
5.	Phototherapy (Light Therapy)