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caudoxin

neurotoxic phospholipase A2 from horned puff adder

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Reptilian Proteins
    - caudoxin: 1
Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Esterases: 1574
      - Carboxylic Ester Hydrolases: 62
        Phospholipases: 2589
        Phospholipases A: 58
        Phospholipases A2: 2075
        Secretory Phospholipases A2: 751
        Group II Phospholipases A2: 123
        caudoxin: 1

Related Diseases

1.

01/01/1986 - "It is concluded that enzyme activity is important for the presynaptic effects of caudoxin, but not for the contracture-inducing action of the Naja nigricollis enzyme. "
01/01/1986 - "Reducing catalytic activity by lowering the incubation temperature or by substitution of Sr2+ for Ca2+ in the bathing medium causes a significant prolongation of the time to neuromuscular block by caudoxin, but does not change the contracture-inducing activity of Naja nigricollis basic phospholipase A2. "
01/01/1986 - "In the chick muscle pretreated with heparin, the latter enzyme fails to evoke contracture, whereas the presynaptic neuromuscular blocking action of caudoxin remains little affected. "
01/01/1986 - "Two toxic phospholipases A2, caudoxin from Bitis caudalis venom and the basic phospholipase A2 from Naja nigricollis venom, were selected for a study of the contribution of enzyme activity and charge properties to the presynaptic neurotoxicity and the contracture-inducing activity of the enzyme. "

Related Drugs and Biologics

1.	Phospholipases A2 (Phospholipase A2)
2.	Venoms
3.	Enzymes
4.	Heparin (Liquaemin)