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4-methylumbelliferyl glucuronide

Also Known As:

4-MUG; 4-methylumbelliferyl-beta-D-glucuronide; hymecromone glucuronide

Networked: 5 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Pyrans: 130
    - Benzopyrans: 195
      - Coumarins: 826
        Umbelliferones: 3
        Hymecromone: 123
        4-methylumbelliferyl glucuronide: 5
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Benzopyrans: 195
      - Coumarins: 826
        Umbelliferones: 3
        Hymecromone: 123
        4-methylumbelliferyl glucuronide: 5

Experts

1.	Bollyky, Paul L: 1 article (10/2019)
2.	Fischer, Jens W: 1 article (10/2019)
3.	Frymoyer, Adam R: 1 article (10/2019)
4.	Grandoch, Maria: 1 article (10/2019)
5.	Gurevich, Irina: 1 article (10/2019)
6.	Kaber, Gernot: 1 article (10/2019)
7.	Kuipers, Hedwich F: 1 article (10/2019)
8.	Malkovskiy, Andrey V: 1 article (10/2019)
9.	Marshall, Payton L: 1 article (10/2019)
10.	Nagy, Nadine: 1 article (10/2019)

Related Diseases

1.	Pancreatic Neoplasms (Pancreatic Cancer) 08/01/2000 - "Comparing the ability of tissue homogenates to cleave the standard substrate 4-methylumbelliferyl-beta-D-glucuronide, we found a significantly increased specific beta-glucuronidase activity (P<0.05) in pancreatic cancer (median: 133; 75% percentile: 286; 25% percentile: 111 nmol/mg per h) as compared to healthy pancreas (median: 74; 75% percentile: 113; 25% percentile: 71 nmol/mg per h). "
2.	Mastitis 10/01/1995 - "The growth of common mastitis-causing bacteria in milk was followed by a fluorometric technique based on the release of fluorescent 4-methylumbelliferone (4-MU) from 4-methylumbelliferyl-beta-D-glucuronide by the beta-glucuronidase of bacterial or milk origin. "
3.	Hepatocellular Carcinoma (Hepatoma) 01/01/2007 - "Therefore, we investigated the effect of these polyphenols on deglucuronidation in rat liver microsomes and in Hepa 1c1c7 mouse hepatoma cells, using 4-methylumbelliferyl glucuronide as model substrate. "
4.	Hemolysis 09/01/2000 - "An algorithm using beta-hemolysis on BAP, lactose reaction on eosin-methylene blue or MacConkey agar, L-pyrrolidonyl-beta-naphthylamide (PYR), and 4-methylumbelliferyl-beta-D-glucuronide (MUG) was evaluated. "
5.	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 10/01/2019 - "We observed that oral administration of 4-MUG to mice inhibits HA synthesis, promotes FoxP3+ regulatory T-cell expansion, and prevents autoimmune diabetes. "

Related Drugs and Biologics

1.	Glucuronidase
2.	Polyphenols
3.	Methylene Blue (Methylthioninium Chloride)
4.	Lactose
5.	Hymecromone
6.	Eosine Yellowish-(YS) (Eosin)
7.	Agar
8.	pyrrolidonyl-beta-naphthylamide

Related Therapies and Procedures

1.	Oral Administration