bis(N-ethylidene vindesine)disulfide

synthetic vinca alkaloid derivative of vinblastine

Also Known As:

bis(N-ethylidene vindesine)disulfide, disulfate; bis-VDS; Vincaleukoblastine, 3,3''-(dithiobis(2,1-ethanediyliminocarbonyl))bis(O4-deacetyl-3-de(methoxycarbonyl))-

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Related Diseases

1.	Leukemia P388 06/01/1982 - "Cultured P388 cells derived from VCR-sensitive P388 leukemia passaged in vivo (P388/0)were significantly more sensitive to VDS and bis-VDS than to VLB. " 06/01/1982 - "Cultured P388 leukemia cells derived from vincristine (VCR)-resistant cell populations developed in vivo in (C57BL X DBA/2)F1 mice (P388/VCR) were cross-resistant to vinblastine (VLB), vindesine (VDS), and bis(N-ethylidene vindesine)disulfide, disulfate (bis-VDS). "
2.	Leukemia 06/01/1982 - "Cross-resistance of cultured murine leukemia vincristine-resistant P388 cells to vinblastine, vindesine, and bis (N-ethylidene vindesine) disulfide, disulfate."

Related Drugs and Biologics

1.	bis(N-ethylidene vindesine)disulfide
2.	Vindesine (Vindesin)
3.	Vincristine (Oncovin)
4.	Vinblastine (Vinblastine Sulfate)