schizandrin A

12/01/2021 - "Schizandrin A ameliorates cognitive functions via modulating microglial polarisation in Alzheimer's disease mice."
01/01/2019 - "The extract of Schisandrin a traditional Chinese medicine was postulated to be effective in prevention and treatment of Alzheimer's disease (AD). "

11/01/2016 - "In the present study, an inflammation model of cells was constructed to confirm the anti-inflammatory effect of deoxyschizandrin. "
01/01/2022 - "Schisandrin A reduced oxidative stress and inflammation in model of DN. "
11/01/2020 - "Evidence of anti-inflammatory activity of Schizandrin A in animal models of acute inflammation."
01/01/2019 - "Schisandrin A Inhibits the IL-1β-Induced Inflammation and Cartilage Degradation via Suppression of MAPK and NF-κB Signal Pathways in Rat Chondrocytes."
01/01/2019 - "In conclusion, this study elucidates that Schisandrin A inhibits the IL-1β-induced inflammation and cartilage degradation via suppression of MAPK and NF-κB signal pathways, indicating its potential role in OA therapy."

05/01/2023 - "Schisandrin A ameliorates increased pulmonary capillary endothelial permeability accompanied with sepsis through inhibition of RhoA/ROCK1/MLC pathways."
05/01/2023 - "Schisandrin A (SchA) is a bioactive lignan which has been reported to have the anti-inflammatory effects in many studies, while whether SchA can ameliorate ALI-related vascular leakage caused by sepsis is unknown. "

01/01/2019 - "Schizandrin A supplementation improves nonalcoholic fatty liver disease in mice fed a high-fat and high-cholesterol diet."
07/01/2023 - "Deoxyschizandrin ameliorates obesity and non-alcoholic fatty liver disease: Involvement of dual Farnesyl X receptor/G protein-coupled bile acid receptor 1 activation and leptin sensitization."

01/01/2013 - "Protective role of deoxyschizandrin and schisantherin A against myocardial ischemia-reperfusion injury in rats."
01/01/1999 - "As a preliminary investigation to exploring whether the methylenedioxy group and the cyclooctadiene ring of the dibenzo[a,c]cyclooctadiene (schisandrin) molecule plays an important role in the protection against myocardial ischemia-reperfusion (IR) injury, we examined the effects of three schisandrins, namely schisandrin A (Sch A), schisandrin B (Sch B), and schisandrin C (Sch C), and the effect of dimethyl-4,-4'-dimethoxy-5,6,5',6'-dimethylene-dioxy-biphenyl-2,2' -bicarboxylate (DDB), an intermediate compound derived from the synthesis of Sch C, on myocardial IR injury in isolated Langendorff-perfused rat hearts. "