cadeguomycin

from Streptomyces hygroscopicus; structure given in first source

Also Known As:

2-amino-3,4-dihydro-4-oxo-7-beta-ribofuranosyl-7H-pyrrolo(2,3-d)pyrimidine-5-carboxylic acid; 7-carboxy-7-deazaguanosine; 1H-Pyrrolo(2,3-d)pyrimidine-5-carboxylic acid, 2-amino-4,7-dihydro-4-oxo-7-beta-D-ribofuranosyl-

Networked: 3 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Purines: 651
      - Purine Nucleosides: 360
        Guanosine: 1156
        cadeguomycin: 3
Nucleic Acids, Nucleotides, and Nucleosides: 1
- Nucleosides: 6847
  - Purine Nucleosides: 360
    - Guanosine: 1156
      - cadeguomycin: 3
  - Ribonucleosides: 49
    - Guanosine: 1156
      - cadeguomycin: 3

Related Diseases

1.	Carcinoma (Carcinomatosis) 04/01/1983 - "Cadeguomycin shows low acute toxicity in mice, enhances DTH reaction, and inhibits Ehrlich ascitic carcinoma in mice. " 05/01/1985 - "Cadeguomycin retarded growth of sc solid IMC carcinoma in CDF1 mice, and pulmonary metastasis of Lewis lung carcinoma in C57BL/6 mice. "
2.	Lewis Lung Carcinoma 05/01/1985 - "Cadeguomycin retarded growth of sc solid IMC carcinoma in CDF1 mice, and pulmonary metastasis of Lewis lung carcinoma in C57BL/6 mice. "
3.	Neoplasms (Cancer) 05/01/1985 - "The results suggest that cadeguomycin inhibits tumor growth and metastasis in association with modification of the immune system. "
4.	Neoplasm Metastasis (Metastasis) 05/01/1985 - "The results suggest that cadeguomycin inhibits tumor growth and metastasis in association with modification of the immune system. " 05/01/1985 - "Cadeguomycin retarded growth of sc solid IMC carcinoma in CDF1 mice, and pulmonary metastasis of Lewis lung carcinoma in C57BL/6 mice. " 05/01/1985 - "The combined administration of arabinosylcytosine and cadeguomycin displayed potentiation in the inhibition of growth of ip-implanted P388 leukemia and metastasis of sc-implanted P388 leukemia to the regional lymph nodes. "
5.	Lymphoma (Lymphomas) 02/01/1987 - "The treatment of K562 human myeloblastic leukemia cells and YAC-1 murine lymphoma cells with cadeguomycin at concentrations over 0.6 microM significantly enhanced the cytotoxicity of 1-beta-D-arabinofuranosylcytosine (ara-C). "

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