bostrycin

04/01/2012 - "Studies on the synthesis of derivatives of marine-derived bostrycin and their structure-activity relationship against tumor cells."
06/01/2020 - "Bostrycin can be used as a new anti-tumor candidate drug for further research. "
02/08/2011 - "Bostrycin is a novel compound isolated from marine fungi that inhibits proliferation of many cancer cells. "
06/01/2020 - "Bostrycin is a natural pigment product with anthraquinone skeleton, which has excellent inhibitory effect on a variety cancer cells. "

02/08/2011 - "This study is to investigate the inhibitory effects and mechanism of bostrycin on human lung cancer cells in vitro. "
02/08/2011 - "However, the inhibitory effect of bostrycin on lung cancers has not been reported. "

05/10/2012 - "This is the first study to show that bostrycin is a promising coupling agent for surface modification on matrix and its potential applications in protein immobilization and biomaterial-centered infection."
05/10/2012 - "Bostrycin, a novel coupling agent for protein immobilization and prevention of biomaterial-centered infection produced by Nigrospora sp. No. 407."

06/01/2020 - "Our study provides reference for the potential application of bostrycin in the treatment of the tongue squamous cell carcinoma."
06/01/2020 - "Bostrycin could inhibit the proliferation and migration of tongue squamous cell carcinoma by arresting cell cycle at G2/M phase, and inducing cell apoptosis with mitochondrial membrane potential changes. "
06/01/2020 - "We studied the effects of bostrycin on the cell growth and apoptosis of tongue squamous cell carcinoma in vitro, and explored its mechanism. "
06/01/2020 - "Bostrycin inhibits growth of tongue squamous cell carcinoma cells by inducing mitochondrial apoptosis."
06/01/2020 - "West-blotting analysis also showed that bostrycin could inhibit the growth of tongue squamous cell carcinoma cells by activating the apoptosis-related signal proteins especially in mitochondrial apoptotic pathway. "

01/01/2016 - "The binding characteristic of MptpB and compound 25 was determined by MST, exhibiting a moderate affinity with a KD constant of 5200 ± 1020 nM. We, for the first time, reported that bostrycin and one of its analogues exhibited inhibitory activity against MptpB, which possessed potential as novel agents against tuberculosis."