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VUFB 13468

structure given in first source

Also Known As:

5-(2-dimethylaminoethoxy)-7-oxo-7H-benzo(c)fluorene; VUFB 13468 hydrochloride; VUFB-13468; benfluron; benflurone; 7H-Benzo(c)fluoren-7-one, 5-(2-(dimethylamino)ethoxy)-

Networked: 7 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 58
- Hydrocarbons: 412
  - Cyclic Hydrocarbons: 3
    - Aromatic Hydrocarbons: 132
      - Aromatic Polycyclic Hydrocarbons: 831
        Fluorenes: 5
        VUFB 13468: 7
Polycyclic Compounds: 56
- Aromatic Polycyclic Hydrocarbons: 831
  - Fluorenes: 5
    - VUFB 13468: 7

Experts

1.	Nobilis, Milan: 1 article (07/2002)
2.	Pichard-Garcia, Lydiane: 1 article (07/2002)
3.	Wsól, Vladimír: 1 article (07/2002)
4.	Maser, Edmund: 1 article (07/2002)
5.	Szotáková, Barbora: 1 article (07/2002)
6.	Savlík, Michal: 1 article (07/2002)
7.	Skálová, Lenka: 1 article (07/2002)
8.	Kondrová, Eliska: 1 article (07/2002)

Related Diseases

1.	Carcinoma (Carcinomatosis) 06/12/1987 - "[The effect of benflurone (VUFB) on the growth of human rectal carcinoma xenotransplanted into athymic nu/nu mice]." 12/11/1991 - "This paper presents data on the effects of benfluron and its two metabolites DBF and NOBF on both endogenous and exogenous, respiration in the presence of succinate as substrate, of both P388 murine leukemia and Ehrlich ascites carcinoma cells. " 01/01/1989 - "The cytolytic activity of two benfluron metabolites, namely 7-dihydrobenfluron (DBF) and benfluron N-oxide (NOBF), has been studied using both Ehrlich ascites carcinoma (EAC) and P388 leukaemia cells. " 01/01/1989 - "The effects of two benfluron metabolites, namely 7-dihydrobenfluron (DBF) and N-oxide of benfluron (NOBF), on the aerobic glycolysis of Ehrlich ascites carcinoma (EAC) and P388 cells were studied. " 01/01/1989 - "Changes in ATP levels of both Ehrlich ascites carcinoma and P388 leukemia cells were evaluated after 2 h of incubation in the presence of different concentrations of benfluron (BF), 7-dihydrobenfluron (DBF) and N-oxide of benfluron (NOBF). "
2.	Ascites 01/01/1989 - "Effects of benfluron metabolites on glycolysis and level of thiol groups in P388 and Ehrlich ascites cells." 12/11/1991 - "Effects of benfluron and its two metabolites on respiratory processes in P388 murine leukemia and Ehrlich ascites cells." 12/11/1991 - "This paper presents data on the effects of benfluron and its two metabolites DBF and NOBF on both endogenous and exogenous, respiration in the presence of succinate as substrate, of both P388 murine leukemia and Ehrlich ascites carcinoma cells. " 01/01/1989 - "The cytolytic activity of two benfluron metabolites, namely 7-dihydrobenfluron (DBF) and benfluron N-oxide (NOBF), has been studied using both Ehrlich ascites carcinoma (EAC) and P388 leukaemia cells. " 01/01/1989 - "The effects of two benfluron metabolites, namely 7-dihydrobenfluron (DBF) and N-oxide of benfluron (NOBF), on the aerobic glycolysis of Ehrlich ascites carcinoma (EAC) and P388 cells were studied. "
3.	Neoplasms (Cancer) 12/11/1991 - "The decrease in the respiratory rates in cancer cells might be due to the effects of benfluron and its metabolites on the cell membrane. " 07/15/2002 - "Benfluron (B, [5-(2-N-oxo-2-N',N"-dimethylaminoethoxy)-7-oxo-7H-benzo[c]fluorene]) is a potential benzo[c]fluorene antineoplastic agent with high activity against a broad spectrum of experimental tumors in vitro and in vivo. " 01/01/1989 - "Effect of benfluron metabolites on ATP level in tumor cells."
4.	Leukemia P388 01/01/1989 - "Changes in ATP levels of both Ehrlich ascites carcinoma and P388 leukemia cells were evaluated after 2 h of incubation in the presence of different concentrations of benfluron (BF), 7-dihydrobenfluron (DBF) and N-oxide of benfluron (NOBF). "
5.	Leukemia 12/11/1991 - "Effects of benfluron and its two metabolites on respiratory processes in P388 murine leukemia and Ehrlich ascites cells." 12/11/1991 - "This paper presents data on the effects of benfluron and its two metabolites DBF and NOBF on both endogenous and exogenous, respiration in the presence of succinate as substrate, of both P388 murine leukemia and Ehrlich ascites carcinoma cells. "

Related Drugs and Biologics

1.	benfluron N-oxide
2.	7-dihydrobenfluron
3.	Aminocaproic Acids (EAC)
4.	Succinic Acid (Succinate)
5.	Adenosine Triphosphate (ATP)
6.	benzo(c)fluorene