octenidine

Also Known As:

LAS-189962; LAS189962; N,N'-(1,10-decanediyldi-1-(4H)-pyridinyl-4-ylidene)bis-(1-octamine) dihydrochloride; Octeniderm; Octenidol; WIN 41,464-6; WIN-41464-2; WIN-41464-6; Win 41464-2; octenidine HCl; octenidine dihydrochloride; octenidine disaccharin; octenidine hydrochloride; octenidine saccharin

Networked: 134 relevant articles (26 outcomes, 36 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Assadian, Ojan: 6 articles (01/2019 - 05/2013)
2.	Kramer, A: 6 articles (05/2016 - 05/2004)
3.	Matiasek, Johannes: 5 articles (01/2021 - 06/2017)
4.	Dilek, Osman Nuri: 5 articles (06/2007 - 01/2004)
5.	Bartoszewicz, Marzenna: 4 articles (10/2021 - 05/2007)
6.	Kramer, Axel: 4 articles (01/2019 - 05/2013)
7.	Akbulut, Gökhan: 4 articles (06/2007 - 01/2004)
8.	Junka, Adam: 3 articles (10/2021 - 01/2021)
9.	Paleczny, Justyna: 3 articles (10/2021 - 01/2021)
10.	Kienzl, Philip: 3 articles (01/2019 - 02/2018)

Related Diseases

1.	Wounds and Injuries (Trauma) 04/15/2019 - "Seven-day treatment with octenidine eradicated bacteria from the wound washouts for 90% of rats and one vascular graft. " 04/15/2019 - "Seven-day treatment course with octenidine eradicated viable bacteria from nine out of 10 wound washouts and sterilized one vascular graft. " 08/01/2016 - "As used in this study, octenidine dihydrochloride proved to be effective and useful, changing the clinical condition of VLU, preparing the wound for future treatment with modern dressings. " 10/17/2023 - "A prospective study to analyse the concentration of octenidine in hand wounds after disinfection by LC-MS/MS." 04/01/2017 - "[Persistent reddening and induration after wound cleansing with octenidine]."
2.	Infections 04/15/2019 - "Further studies are needed to investigate if irrigations with octenidine could properly cure vascular bed from infection to assure a successful implantation of a new synthetic vascular substitute." 05/09/2023 - "Patients treated preoperatively with the octenidine dihydrochloride protocol showed lower early infection rates. " 08/13/2015 - "Combined with a favourable safety and tolerability profile, octenidine-based products thus represent a good choice in multifaceted MRSA decontamination regimes, which are necessary to curb the increasing problem of severe infections." 09/08/2022 - "Evaluating the effectiveness of octenidine-containing wash mitts in reducing infections in intensive care." 11/01/2018 - "Octenidine is frequently used for infection prevention in neonatal and burn intensive care units, where Pseudomonas aeruginosa has caused nosocomial outbreaks. "
3.	Cicatrix (Scar) 07/01/2016 - "Skin complications including blistering, necrosis and scarring were seen with all octenidine products, a fact which has not been previously reported." 01/01/2021 - "Octenidine dihydrochloride (OCT) is a widely used antiseptic molecule, promoting skin wound healing accompanied with improved scar quality after surgical procedures. " 12/01/2018 - "An octenidine-based hydrogel has been shown to modulate immunological function in an in vitro wound model, suggesting an improved scar formation. " 12/01/2018 - "An intra-individual surgical wound comparison shows that octenidine-based hydrogel wound dressing ameliorates scar appearance following abdominoplasty."
4.	Leg Ulcer 05/01/2015 - "Patients suffering from chronic leg ulcers were treated in a clinical controlled monocentric trial with either APP or octenidine (OCT). " 08/01/2016 - "To assess the impact of a two-period treatment on the clinical condition, bacteriological changes and results of treatment of venous leg ulcers (VLU) using octenidine dihydrochloride. " 04/01/2016 - "The aim of this study was to determine the efficacy, safety and cost-effectiveness of an octenidine-based wound gel in the treatment of chronic venous leg ulcers. " 04/01/2016 - "As a result, the octenidine wound gel is cost-effective and well suitable for the treatment of chronic venous leg ulcers, considering both safety and promotion of wound healing. " 04/01/2016 - "Efficacy and cost-effectiveness of octenidine wound gel in the treatment of chronic venous leg ulcers in comparison to modern wound dressings."
5.	Sepsis (Septicemia) 01/01/2016 - "To investigate the effect of universal decolonization with octenidine on the incidence of ICU-acquired bloodstream infections (BSI) and MDR organisms (MDRO). " 01/01/2016 - "An observational study of the universal use of octenidine to decrease nosocomial bloodstream infections and MDR organisms." 06/01/2010 - "Patients treated with octenidine had a non-significant reduction in catheter-associated bloodstream infections (4.1% vs. 8.3%; OR = 0.44; 95%CI: 0.18-1.08, p 0.081). " 06/01/2013 - "Catheter related sepsis was 10.5% in the povidone iodine and octenidine hydrochlorodine groups. " 01/01/2023 - "Central-line associated bloodstream infections in intensive care units before and after implementation of daily antiseptic bathing with chlorhexidine or octenidine: a post-hoc analysis of a cluster-randomised controlled trial."

Related Drugs and Biologics

1.	Local Anti-Infective Agents (Antiseptics)
2.	polihexanide
3.	Povidone-Iodine (Betadine)
4.	Hypochlorous Acid (Hypochlorite)
5.	Chlorhexidine
6.	phenoxyethanol (2-phenoxyethanol)
7.	Solutions
8.	chlorhexidine gluconate (Dyna-Hex)
9.	Gentamicins (Gentamicin)
10.	Hydrogels

Related Therapies and Procedures

1.	Abdominoplasty
2.	Catheters
3.	Operative Surgical Procedures
4.	Therapeutics
5.	Sutures (Suture)