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poly(lactide) (polylactide)

Subscribe to New Research on poly(lactide)

RN refers to homopolymer & (DL)-isomer

Also Known As:

polylactide; 70-30 poly-L-lactide-Co-D,L-lactide; PLA96; PolyMax; Resomer R208; Resorb-X; SR PLA96; SR-PLA96; hydrosorb; poly(D,L-lactide); poly(DL-lactide); poly(L-lactide); poly(L-lactide-co-D,L-lactide); poly(lactide), (L)-isomer; poly(rac-lactide); poly-96L 4D-lactide; poly-L-D-lactide; poly-L-lactide; ticron

Networked: 321 relevant articles (22 outcomes, 63 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Cui, Wenguo: 5 articles (06/2015 - 01/2013)
2.	Evora, C: 5 articles (04/2008 - 07/2000)
3.	Khuller, G K: 5 articles (12/2004 - 01/2001)
4.	Törmälä, P: 5 articles (09/2002 - 01/2000)
5.	Huang, Yubin: 4 articles (07/2015 - 06/2012)
6.	Jing, Xiabin: 4 articles (07/2015 - 06/2012)
7.	Kellomäki, Minna: 4 articles (01/2015 - 12/2005)
8.	Hwang, Jeong-Min: 4 articles (10/2009 - 06/2006)
9.	Choung, Ho-Kyung: 4 articles (10/2009 - 06/2006)
10.	Kim, Chong-Kook: 4 articles (10/2009 - 06/2006)

Related Diseases

1.	Neoplasms (Cancer) 10/07/2015 - "The hydrophobicity of poly(L-lactide) was increased by copolymerization with cell-membrane-lipid components, and this significantly enhanced the uptake of NPs up to 60% in the human cervical cancer cell line in comparison to unmodified poly(L-lactide) NPs." 02/01/2015 - "Poly-L-Lactide (PLA), a bioabsorbable prosthetic material, has been used in the plate form for reconstruction after tumor resection in children. " 05/01/2013 - "Drug release kinetics, cell uptake, and tumor toxicity of hybrid VVVVVVKK peptide-assembled polylactide nanoparticles." 02/01/2007 - "[Comparison of preparing two polylactide nanoparticles loaded lipophilic anti-cancer herb drug by nanoprecipitation method]." 01/01/1994 - "Poly-L-lactide (PLLA) plates, 20 x 10 x 1 mm in size, with flat surfaces, were implanted into 50 young male Wistar rats subcutaneously, and the incidence of tumors for 2 years under specific pathogen-free (SPF) conditions was evaluated. "
2.	Infection 03/05/2001 - "The aim of the present study was to compare the resistance to infection of two polylactide implants with different degradation characteristics, and to evaluate the influence of a bacterial challenge on their mechanical and physicochemical properties. " 12/01/2005 - "In the PLA96 group, acute or chronic infections occurred in four rabbits. " 07/01/2005 - "Poly(D,L-lactide) coating of Schanz' screws does not prevent osseous destruction and severe bacterial colonization along the pin tracts, but can improve osseous integration of Schanz' screws in the absence of infection." 07/01/2005 - "Poly(D,L-lactide) coating is capable of enhancing osseous integration of Schanz screws in the absence of infection." 01/01/2014 - "This study was designed for Ibuprofen (IBU)-loaded poly(L-lactide) (PLLA) electrospun fibrous membranes containing a low dosage of Ag to evaluate its potential in maintaining suitable anti-infection and good anti-adhesion effects. "
3.	Osteomyelitis 05/01/2003 - "The objective of this study was to evaluate the efficacy of a new biodegradable, gentamicin-loaded poly(D,L-lactide) (PDLLA) coating of orthopedic devices in preventing implant-related osteomyelitis. " 04/01/2011 - "Experimental osteomyelitis caused by methicillin-resistant Staphylococcus aureus treated with a polylactide carrier releasing linezolid." 07/31/2000 - "Implants to prevent or treat osteomyelitis are described, composed of phosphate/poly(d,l-lactide) blends containing the antibiotic gentamicin. " 10/01/1994 - "Polylactide/polyglycolide antibiotic implants in the treatment of osteomyelitis. " 11/01/2007 - "We developed a local drug-release system consisting of two biodegradable polymers, poly(sebacic anhydride) (PSA) and poly-D,L-lactide (PLA), for the treatment of chronic osteomyelitis. "
4.	Wounds and Injuries (Trauma) 07/07/2014 - "In an experimental animal wound model, the polylactide membranes showed faster wound closure, indicating its use as a passive dressing material. " 06/01/1995 - "We tested the hypothesis that porous D,L-polylactide implanted in a standard intraosseous calvarial wound would not hinder but would support bone regeneration. " 07/01/1988 - "Composite grafts also were tested: 1) a two-layer graft, 2) an alternating layers graft, and 3) a D,L-epsilon graft reinforced with circumferentially wound poly-L-lactide fibers. " 06/10/2010 - "Additionally, Hydrosorb provides a cushioning effect for wound protection, and has a soothing and cooling effect on superficial burns. " 03/01/2007 - "Both acute and chronic wounds can be effectively treated with the Hydrosorb comfort hydrogel dressing."
5.	Tibial Fractures (Fracture, Tibial) 03/01/1997 - "The objective of this study was to compare the efficacy of biodegradable, poly (DL-lactide-co-glycolide) cefazolin microspheres and free cefazolin powder in Staphylococcus aureus contaminated rabbit tibial fractures when treatment was delayed for 2 hours. " 06/01/2005 - "Due to reports of possible foreign body reactions caused by polymer materials in orthopedic surgery, this study investigated the biocompatibility of the polylactide implant coating and the locally released growth factors during the time course of rat tibial fracture healing (days 5, 10, 15, and 28 after fracture). "

Related Drugs and Biologics

1.	Carbon Monoxide
2.	polylactic acid-polyglycolic acid copolymer (PLGA)
3.	Ethylene Glycol (Monoethylene Glycol)
4.	Cefazolin (Ancef)
5.	Antitubercular Agents
6.	Paclitaxel (Taxol)
7.	Polymers
8.	Polyglycolic Acid (Polyglycolide)
9.	Gentamicins (Gentamicin)
10.	Antigens

Related Therapies and Procedures

1.	Microspheres (Microsphere)
2.	Injections
3.	Drug Therapy (Chemotherapy)
4.	Arthrodesis
5.	Tenodesis