puerarin

12/05/2013 - "This study was to investigate whether activating the cholinergic anti-inflammatory pathway can be involved in the mechanism of inhibiting the inflammatory response during puerarin-induced cerebral ischemia/reperfusion in rats. "
02/23/2005 - "Another novel finding of this study was that the elimination rate of puerarin was significantly slower in the cerebral ischemia reperfusion rat than in the normal rat, judging by the pharmacokinetic parameters obtained. "
02/23/2005 - "HPLC method for the determination and pharmacokinetic studies on puerarin in cerebral ischemia reperfusion rat plasma after intravenous administration of puerariae radix isoflavone."
05/01/2014 - "Puerarin, a major active ingredient extracted from the traditional Chinese plant medicine Ge-gen, has been widely used in treatment of myocardial and cerebral ischemia. "
04/01/2014 - "Puerarin protected the brain from cerebral ischemia injury via astrocyte apoptosis inhibition."

06/13/2006 - "The aim of the present study was to determine whether the clinically effective cardioprotection conferred by puerarin (Pue) against ischemia and reperfusion is mediated by mitochondrial transmembrane pores and/or channels. "
01/01/2005 - "The aim of the present study was to determine whether the clinically effective cardioprotection conferred by puerarin (Pue) against ischemia and reperfusion is mediated by mitochondrial transmembrane pores and/or channels. "
03/01/2005 - "To study the protection of puerarin on the cerebral injury in the rats with acute local ischemia. "
01/01/2013 - "lobata (TIPL), which contains the unique isoflavone puerarin, in ischemia in vivo models. "
02/01/2009 - "In the puerarin group, the number of apoptotic cells decreased at respective time points after ischemia-reperfusion (P<0.01). "

01/05/2016 - "The results indicated that puerarin markedly inhibited Ni-induced liver injury, which was characterized by decreased aminotransferase activities and inflammation. "
02/01/2015 - "Puerarin attenuates airway inflammation by regulation of eotaxin-3."
09/01/2014 - "Altogether, these results suggest that puerarin could protect the CCl4-induced oxidative stress and inflammation by ERK/Nrf2/ARE pathway. "
08/01/2010 - "Puerarin (4'-7-dihydroxy-8-beta-D-glucosylisoflavone), the most abundant isoflavone-C-glucoside extracted from the root of the plant Pueraria lobata, has demonstrated anti-inflammatory activity in cellular models of inflammation. "
02/01/2013 - "Puerarin mediates hepatoprotection against CCl4-induced hepatic fibrosis rats through attenuation of inflammation response and amelioration of metabolic function."

01/01/2014 - "We found that consecutive intrathecal administration of puerarin (4-100 nM) for 7 days inhibited the mechanical and thermal nociceptive response induced by CCI and diabetes without interfering with the normal pain response. "
06/01/2013 - "In the present study, the effect of puerarin, an active ingredient extracted from Chinese herbal medicine Ge Gen, on pain relief of burn patients during dressing change and the mechanism related to the regulation of the purinergic signalling pathway were investigated. "
07/01/2014 - "The beneficial effects of puerarin on the various medicinal purposes may be due to its wide spectrum of pharmacological properties such as vasodilation, cardioprotection, neuroprotection, antioxidant, anticancer, antiinflammation, alleviating pain, promoting bone formation, inhibiting alcohol intake, and attenuating insulin resistance. "
06/01/2013 - "Effects of puerarin on the inflammatory role of burn-related procedural pain mediated by P2X(7) receptors."
12/01/2011 - "Thus, puerarin had an analgesic effect on procedural pain in dressing changes of burn patients related to P2X(3) receptors."

01/01/2015 - "This study was designed to explore the mechanism of puerarin in treatment of acute spinal ischemia-reperfusion injury in rats. "
06/01/1992 - "To ascertain the beneficial effect of puerarin on the myocardium against reperfusion injury, studies on myocardial metabolism and ultrastructure were made. "
04/01/2015 - "Astragaloside's PRC value was significantly higher than those of FA and puerarin between 120 to 180 min. The pharmacokinetics of FA-Pr-Al in combination were closely related its pharmacodynamics in treating ischemia/reperfusion injury, and the components of FA-Pr-Al may have a synergistic pharmacological effect. "
01/01/2013 - "It is well known that puerarin attenuates ischemia-reperfusion injury and promotes function recovery of ischemic region. "
04/12/2011 - "The spinal ischemia-reperfusion injury was conducted in male Sprague-Dawley rats, and 50mg/kg of puerarin was injected intraperitoneally at 1, 2, 4 and 6h after the injury. "