beta-1,3-glucan

component of fungal cell walls; also used as antitumor polysaccharide; unspecified D usually means BETA-GLUCANS; beta-1,3-D-glucan is also available; glucan phosphate is also available; biosynthesis is inhibited by echinocandins (cyclic hexapeptides)

Also Known As:

Networked: 39 relevant articles (0 outcomes, 2 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Bae, Hyocheol: 1 article (03/2020)
2.	Chang, Moon-Jeong: 1 article (03/2020)
3.	Hong, Taeyeon: 1 article (03/2020)
4.	Lee, Jin-Young: 1 article (03/2020)
5.	Lim, Whasun: 1 article (03/2020)
6.	Song, Gwonhwa: 1 article (03/2020)
7.	Liu, Ruting: 1 article (01/2020)
8.	Shen, Zhongyuan: 1 article (01/2020)
9.	Tang, Xudong: 1 article (01/2020)
10.	Zhang, Yiling: 1 article (01/2020)

Related Diseases

1.	Infections 02/01/2001 - "During sclerotial infection of Sclerotinia sclerotiorum the mycoparasite Coniothyrium minitans penetrates through the host cell wall, which contains beta-1,3-glucan as its major component. " 06/01/1998 - "Beta-1,3-glucan is a potent stimulator of macrophage functions and has a protective effect against a range of infections in rodent models. " 03/01/2016 - "Beta-1,3-glucan (BG) protects against infection and shock by activating immune cells. " 01/01/2020 - "Most proteins involved in basic metabolism were up-regulated following infection, and the expression levels of some proteins related to the host immunity, such as the lipid droplet protein prilipin, 30 K proteins, HDD13, and beta-1,3-glucan recognition protein, were altered after infection with N. " 07/01/2005 - "Deposition of beta-1,3-glucan callose at infection sites was specifically impaired in er-1 and agb1-1 mutants upon P. "
2.	Wounds and Injuries (Trauma) 08/15/2003 - "Plants attacked by pathogens rapidly deposit callose, a beta-1,3-glucan, at wound sites. " 10/01/2002 - "Soluble beta-1,3-glucan has been demonstrated to protect against infection and shock in rats and mice, and clinical studies suggest that administration of soluble glucans to trauma/surgical patients decreases septic complications and improves survival. "
3.	Shock 03/01/2016 - "Beta-1,3-glucan (BG) protects against infection and shock by activating immune cells. " 10/01/2002 - "Soluble beta-1,3-glucan has been demonstrated to protect against infection and shock in rats and mice, and clinical studies suggest that administration of soluble glucans to trauma/surgical patients decreases septic complications and improves survival. "
4.	Body Weight (Weight, Body) 09/01/2009 - "The study of the major 56-kDa polysaccharide, laetiporan A, the content of which accounted for 0.28% of the fruiting body weight, showed that it is a beta-1,3-glucan containing mannose, galactose, fucose, xylose, and rhamnose residues at position C-6. "
5.	Cysts 10/01/1994 - "carinii cyst wall, but beta-1,3-glucan was absent from intracystic bodies and trophozoites. " 08/01/1990 - "carinii is related to fungi and that the wall of the cyst form contains 1,3-beta-glucan as a major constituent. " 09/01/2010 - "Pneumocandins inhibit beta-1,3-glucan synthesis preventing the development of Pneumocystis cysts that are absent from the lungs of treated rats. " 09/27/2007 - "Caspofungin, a beta-1,3-glucan synthesis inhibitor, has shown activity against the cyst forms of P. " 12/22/2000 - "carinii contains a unique catalytic subunit of beta-1,3-glucan synthetase utilized in cyst wall formation. "

Related Drugs and Biologics

1.	Polysaccharides (Glycans)
2.	Xylose (D-Xylose)
3.	Rhamnose
4.	Mannose (D-Mannose)
5.	Glucans
6.	Galactose (Galactopyranose)
7.	Fucose
8.	Echinocandins
9.	callose
10.	laminaran

Related Therapies and Procedures

1.	Laparotomy
2.	Therapeutics
3.	Intravenous Infusions