NSC 297170

RN given refers to cpd without isomeric designation; structure in first source

Also Known As:

1,2-diethyl-1,2-bis(3'-hydroxyphenyl)ethane; 3,3'-HES; 3,4-bis(3'-hydroxyphenyl)hexane; NSC 297170, (R*,R*)-(+-)-isomer; NSC 297170, (R*,S*)-isomer; NSC-297170; meso-3,4-bis(3'-hydroxyphenyl)hexane; metahexestrol

Networked: 2 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Benzene Derivatives: 17
        Benzylidene Compounds: 10
        Stilbenes: 657
        Dihydrostilbenoids: 5
        Hexestrol: 29
        NSC 297170: 2
        Stilbestrols: 1
        Hexestrol: 29
        NSC 297170: 2
        Benzyl Compounds: 2
        Bibenzyls: 16
        Dihydrostilbenoids: 5
        Hexestrol: 29
        NSC 297170: 2

Related Diseases

Neoplasms (Cancer)

01/01/1982 - "It cannot be decided whether the partial antiestrogen, 3,4-bis(3'-hydroxyphenyl)hexane unfolds its antimammary tumor activity by means of its estrogenic or its antiestrogenic potency. "
05/01/1984 - "The syntheses of symmetrically 4,4'-, 5,5'-, and 6,6'-disubstituted derivatives of the mammary tumor inhibiting antiestrogen metahexestrol [meso-3,4-bis(3-hydroxyphenyl)hexane] (1) are described [4,4'-substituents: F, (2), Cl (3), Br (4), I (5), CH2N (CH3)2 (6), CH3 (7), CH2OCH3 (8), CH2OC2H5 (9), CH2OH (10), NO2 (11), NH2 (12), N(CH3)2 (13), COCH3 (14), and C2H5 (15); 5,5'-substituents: OH (16) and Cl (17); 6,6'-substituents: OH (18), F (19), Cl (20), and CH3 (21)]. "
01/01/1982 - "Biochemical properties, such as the activities of eight carbohydrate-metabolism-linked enzymes and four acid hydrolases, and histological characteristics of growing and regressing DMBA-induced mammary tumors of the SD-rat after ovariectomy or treatment of the host with hexesterol, tamoxifen, and 3,4-bis(3'-hydroxyphenyl)hexane were determined. "

Related Drugs and Biologics

1.	Estrogen Receptor Modulators (Antiestrogen)
2.	Tamoxifen
3.	Hydrolases
4.	Hexanes
5.	Enzymes
6.	Acids
7.	hydroxide ion

Related Therapies and Procedures

1.	Ovariectomy (Oophorectomy)