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macrophage migration inhibitory factor receptor

Also Known As:

MIF receptor; MMIF receptors; receptor, macrophage migration inhibitory factor

Networked: 20 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - Cell Surface Receptors: 2125
      - Immunologic Receptors: 9
        macrophage migration inhibitory factor receptor: 20

Experts

1.	Bucala, Richard: 7 articles (01/2021 - 01/2011)
2.	Leng, Lin: 6 articles (01/2021 - 01/2011)
3.	Meyer-Siegler, Katherine L: 3 articles (01/2021 - 05/2008)
4.	Vera, Pedro L: 3 articles (01/2021 - 05/2008)
5.	Sauler, Maor: 3 articles (12/2016 - 03/2014)
6.	Hunt, David E: 2 articles (01/2021 - 01/2015)
7.	Ma, Fei: 2 articles (01/2021 - 01/2015)
8.	Du, Xin: 2 articles (12/2016 - 01/2011)
9.	Lee, Patty J: 2 articles (05/2015 - 03/2014)
10.	Shan, Peiying: 2 articles (05/2015 - 03/2014)

Related Diseases

1.	Neoplasms (Cancer) 07/01/2015 - "The macrophage migration inhibitory factor (MIF) receptor CD74 is overexpressed in various neoplasms, mainly in hematologic tumors, and currently investigated in clinical studies. "
2.	Systemic Lupus Erythematosus (Libman-Sacks Disease) 01/01/2011 - "These data highlight the feasibility of targeting the MIF-MIF receptor interaction by small-molecule antagonism and support the therapeutic value of downregulating MIF-dependent pathways of tissue damage in systemic lupus erythematosus." 01/01/2021 - "Experience with milatuzumab, an anti-CD74 antibody against immunomodulatory macrophage migration inhibitory factor (MIF) receptor, for systemic lupus erythematosus (SLE)."
3.	Inflammation (Inflammations) 05/01/2008 - "Previous findings showed that acute bladder inflammation increased MIF release into the bladder lumen while upregulating MIF and CD74 (MIF receptor) in the bladder. " 01/01/2015 - "Bladder PAR activation elicits urothelial MIF release and urothelial MIF receptor signaling at least partly through CXCR4 to result in abdominal hypersensitivity without overt bladder inflammation. "
4.	Infections 01/01/2022 - "Both ILC2s and macrophages expressed the MIF receptor CXCR4, indicating that MIF may act as an essential co-factor on both cell types to activate responses to IL-25 in helminth infection." 01/01/2016 - "Our results add to the current understanding on SINV disease and raise questions of a potential role of uncleaved PE2 and the MIF receptor (CD74) mimotope in human SINV infection."
5.	Hyperalgesia 01/01/2021 - "We tested the effect of intravesical pre-treatment with individual MIF or MIF receptor (CD74, CXCR4, CXCR2) antagonists on PAR4-induced HMGB1 release in vivo (female C57/BL6 mice) and in vitro (primary human urothelial cells) and on PAR4-induced bladder hyperalgesia in vivo (mice). " 01/01/2015 - "Female C57BL/6 mice received intravesical PAR1- or PAR4-AP for one hour to determine: 1) bladder MIF release in vivo within one hour; 2) abdominal hypersensitivity (allodynia) to von Frey filament stimulation 24 hours after treatment; 3) micturition parameters 24 hours after treatment; 4) histological changes in the bladder as a result of treatment; 5) changes in expression of bladder MIF and MIF receptors using real-time RT-PCR; 6) changes in urothelial MIF and MIF receptor, CXCR4, protein levels using quantitative immunofluorescence; 7) effect of MIF or CXCR4 antagonism. "

Related Drugs and Biologics

1.	Macrophage Migration-Inhibitory Factors
2.	Osteoprotegerin
3.	Fas Ligand Protein (Fas Ligand)
4.	TNF-Related Apoptosis-Inducing Ligand
5.	Capsid Proteins (Capsid Protein)
6.	HMGB1 Protein (HMG1)
7.	fas Receptor (CD95 Antigen)
8.	Proteins (Proteins, Gene)
9.	Epitopes
10.	Amino Acids

Related Therapies and Procedures

1.	Aftercare (After-Treatment)