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preprocalcitonin

calcitonin with 20 amino acid extension beyond carboxyl terminal proline

Also Known As:

Calcitonin, prepro-

Networked: 7 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Mami-Chouaib, Fathia: 3 articles (01/2019 - 07/2008)
2.	Chouaib, Salem: 2 articles (01/2019 - 07/2008)
3.	El Hage, Faten: 2 articles (04/2013 - 07/2008)
4.	Guillebot De Nerville, Guillaume: 1 article (01/2019)
5.	Leclerc, Marine: 1 article (01/2019)
6.	Malenica, Ines: 1 article (01/2019)
7.	Mezquita, Laura: 1 article (01/2019)
8.	Tihy, Isabelle: 1 article (01/2019)
9.	Durgeau, Aurélie: 1 article (04/2013)
10.	Baurain, Jean-François: 1 article (07/2008)

Related Diseases

1.	Thyroid Neoplasms (Thyroid Cancer) 03/01/2001 - "Induction of a cellular and humoral immune response against preprocalcitonin by genetic i: a potential new treatment for medullary thyroid carcinoma." 04/01/1983 - "Medullary thyroid carcinomas secrete a noncalcitonin peptide corresponding to the carboxyl-terminal region of preprocalcitonin." 10/10/1983 - "Glucocorticoids stimulate the production of preprocalcitonin-derived secretory peptides by a rat medullary thyroid carcinoma cell line."
2.	Neoplasms (Cancer) 01/01/2023 - "Differential gene expression analysis revealed elevated expression of CALCA (preprocalcitonin) and CCDC183 (highly expressed in testes) in patients who experienced clinical activity, suggesting that tumor neoantigens from these genes may contribute to immune response. " 01/01/2019 - "In this context, we previously identified a non-mutant tumor neoepitope, ppCT16-25, derived from the preprocalcitonin (ppCT) leader sequence and processed independently of proteasomes/TAP by a mechanism involving signal peptidase (SP) and signal peptide peptidase (SPP). " 07/22/2008 - "Preprocalcitonin signal peptide generates a cytotoxic T lymphocyte-defined tumor epitope processed by a proteasome-independent pathway."
3.	Carcinoma (Carcinomatosis) 04/01/2013 - "We identified that the antigen preprocalcitonin (ppCT) is recognized on a human lung carcinoma by a cytotoxic T lymphocyte clone derived from autologous tumor-infiltrating lymphocytes. "

Related Drugs and Biologics

1.	Peptides (Polypeptides)
2.	Proteasome Endopeptidase Complex (Proteasome)
3.	Protein Sorting Signals (Signal Peptide)
4.	Glucocorticoids
5.	Antigens
6.	Epitopes
7.	signal peptide peptidase
8.	type I signal peptidase (signal peptidase)