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decamethonium (decamethonium bromide)

RN given refers to parent cpd
Also Known As:
decamethonium bromide; (DM)Br2; decamethonium dibromide; decamethonium dichloride; decamethonium dihydroxide; decamethonium diiodide; decamethonium dipricrate; decamethonium iodide; decamethylenebis(trimethylammonium)bromide
Networked: 54 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Drug Context: Research Results

Experts

1. Kunselman, Allen: 1 article (01/2021)
2. Murphy, Paula: 1 article (01/2021)
3. Peterson, Benjamin E: 1 article (01/2021)
4. Rolfe, Rebecca A: 1 article (01/2021)
5. Szczesny, Spencer E: 1 article (01/2021)
6. Dilger, James P: 1 article (01/2019)
7. Goswami, Lalit N: 1 article (01/2019)
8. Hawthorne, M Frederick: 1 article (01/2019)
9. Jalisatgi, Satish S: 1 article (01/2019)
10. Johnson, Quinn L: 1 article (01/2019)

Related Diseases

1. Myasthenia Gravis
2. Respiratory Insufficiency (Respiratory Failure)
3. Neuromuscular Diseases (Neuromuscular Disease)
4. Paralysis (Palsy)
5. Ganglion Cysts (Ganglion)
01/01/1980 - "In order to examine the applicability of this method, we chose the excitatory type of acetylcholine-induced responses of the ganglion cells in Aplysia, and analyzed the mode of inhibition by decamethonium (Deca) and tetraethylammonium (TEA). "
11/01/1986 - "The blocking properties of tubocurarine, decamethonium, hexamethonium and trimetaphan on nicotinic agonists applied by repetitive ionophoretic pulses were examined in rat submandibular ganglion cells using a two-microelectrode voltage-clamp technique at 30 degrees C. "
03/01/1970 - "1. When the movement of the nictitating membrane is recorded in the usual way, pulled out under load in cat, dog, or rabbit, end-plate-depolarizing drugs such as succinylcholine, decamethonium, nicotine, and 2268F, cause a retraction.2. This movement is due to activation of orbital striated muscle, as evidenced by the resistance of the movement to ganglion block or excision of the superior cervical ganglion and to administration of phentolamine or atropine, and by its great sensitivity to dimethyltubocurarine.3. End-plate-depolarizing drugs produce contractions of the superior and inferior oblique and of the recti muscles strong enough to account for the movements of the nictitating membrane, provided the known fascial connexions of the orbit allow transmission of a fraction of the extraocular muscle movement to the membrane.4. In post mortem specimens with the front of the orbit undisturbed, retraction of the central end of any of the ocular muscles produces movement of the nictitating membrane; the movement was greatest with the superior oblique and medial rectus. "
09/01/1969 - "1. The ganglion blocking agents, chlorisondamine, pentamethonium, mecamylamine, decamethonium and hexamethonium all block nicotine extensor convulsions when administered intraventricularly in mice. "

Related Drugs and Biologics

1. Cholinesterase Inhibitors (Anticholinesterases)
2. Succinylcholine (Suxamethonium Chloride)
3. Potassium
4. Neuromuscular Depolarizing Agents
5. Tubocurarine (Tubocurarine Chloride)
6. Acetylcholine (Acetylcholine Chloride)
7. Gallamine Triethiodide (Gallamine)
8. Pancuronium (Pavulon)
9. Nicotine
10. Neuromuscular Blocking Agents

Related Therapies and Procedures

1. Orthopedic Procedures
2. Positive-Pressure Respiration (Positive End-Expiratory Pressure)
3. Microelectrodes
4. Intravenous Injections
5. Injections