hydrocortisone 17-butyrate 21-propionate

RN given for (11beta)-isomer; structure in first source

Also Known As:

hydrocortisone buteprate; Pandel

Networked: 7 relevant articles (0 outcomes, 2 trials/studies)

Drug Context: Research Results

Polycyclic Compounds: 6
- Fused-Ring Compounds
  - Steroids: 70059
    - Pregnanes: 9
      - Pregnenes: 1
        Pregnenediones
        Hydrocortisone: 24422
        hydrocortisone 17-butyrate 21-propionate: 7
Hormones, Hormone Substitutes, and Hormone Antagonists
- Hormones: 80400
  - Adrenal Cortex Hormones: 62914
    - Hydroxycorticosteroids: 7
      - 17-Hydroxycorticosteroids: 179
        Hydrocortisone: 24422
        hydrocortisone 17-butyrate 21-propionate: 7
      - 11-Hydroxycorticosteroids: 56
        Hydrocortisone: 24422
        hydrocortisone 17-butyrate 21-propionate: 7

Experts

1.	Jeyakanthan, Jeyaraman: 1 article (02/2020)
2.	Mohanapriya, Arumugam: 1 article (02/2020)
3.	Nanda, Harshit: 1 article (02/2020)
4.	Odumpatta, Rajasree: 1 article (02/2020)
5.	Ponnusamy, Nirmaladevi: 1 article (02/2020)
6.	Abeck, D: 1 article (03/2016)
7.	Fölster-Holst, R: 1 article (03/2016)
8.	Torrelo, A: 1 article (03/2016)

Related Diseases

1.	Phototoxic Dermatitis (Phototoxicity) 07/01/1981 - "[Studies on antigenicity, phototoxicity and other specific toxicities of hydrocortisone 17-butyrate 21-propionate (HBP) (author's transl)]."
2.	Atopic Dermatitis (Atopic Eczema) 07/01/1997 - "This multicenter, double-masked, placebo-controlled, randomized study evaluated the efficacy, safety, tolerability, and cosmetic acceptability of hydrocortisone buteprate 0.1% cream in the treatment of patients with atopic dermatitis. " 07/01/1997 - "One hundred ninety-four adults with clinically diagnosed atopic dermatitis were randomized to treatment with hydrocortisone buteprate 0.1% cream or placebo (the cream base of the medication) applied topically once daily for 14 days. " 07/01/1997 - "Efficacy and safety of hydrocortisone buteprate 0.1% cream in patients with atopic dermatitis."
3.	Skin Diseases (Skin Disease) 03/01/2016 - "Topical hydrocortisone 17-butyrate 21-propionate in the treatment of inflammatory skin diseases: pharmacological data, clinical efficacy, safety and calculation of the therapeutic index."
4.	Psoriasis (Pustulosis Palmaris et Plantaris) 02/01/2020 - "Therefore, the drug pandel could be explored further and repurposed to treat psoriasis."
5.	Hypersensitivity (Allergy) 11/01/1991 - "In the case of dermal application of the drugs to croton oil-induced ear edema in rats and picryl chloride-induced delayed type hypersensitivity in mice, the anti-inflammatory effect of methylprednisolone aceponate (MPA) was slightly weaker than those of clobetasol 17-propionate and diflucortolone 21-valerate, but stronger than those of hydrocortisone 17-butyrate and hydrocortisone 17-butyrate 21-propionate. "

Related Drugs and Biologics

1.	Clobetasol (Clobetasol Propionate)
2.	Steroids
3.	Picryl Chloride (Trinitrochlorobenzene)
4.	Ointments (Pastes)
5.	Diflucortolone
6.	Croton Oil
7.	methylprednisolone aceponate
8.	diflucortolone valerate
9.	hydrocortisone-17-butyrate (Locoid)