canatoxin
toxic protein from Canavalia ensiformis (jack bean) seeds; distinct from concanavalin A
Networked: 9
relevant articles (0 outcomes,
1 trials/studies)
Bio-Agent Context: Research Results
Experts
Related Diseases
1. | Hypoxia (Hypoxemia)
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2. | Hypoglycemia (Reactive Hypoglycemia)
09/01/1993
- " The hyperinsulinemic response to canatoxin was greater in females (+108 +/- 18%) than males (+43 +/- 8%), but no difference was noted in the hypoglycemia. " 01/01/1989
- " 2. Chronic administration of canatoxin (50 mU, ip, daily for 3 days) induced hypoglycemia in female rats (N = 6) (-36.54 +/- 3.24%, P less than 0.05). " 01/01/1986
- " After administration of subconvulsant doses of canatoxin the rats showed initially hyperglycemia during the first 30 min, followed by a long-lasting hypoglycemia. " 09/01/1993
- " Canatoxin, a proteic neurotoxin from Canavalia ensiformis seeds, raises circulating insulin levels and induces hypoglycemia in rats. " 01/01/1989
- " 4. Gonadal steroid replacement (testosterone, 10 mg/kg, im) for gonadectomized male rats did not reverse the inhibition of canatoxin-induced blood glucose alterations, whereas pretreatment of intact female rats (N = 6) with testosterone (10 mg/kg, im) significantly attenuated the canatoxin-induced hypoglycemia. "
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3. | Hyperglycemia
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4. | Hyperinsulinism (Hyperinsulinemia)
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5. | Edema (Dropsy)
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