chlorodibromomethane

01/01/2004 - "Among the 19 districts, people living in Sai Kung have the highest risk of cancer due to the THM exposure through the multipathways, mainly because of the exposure to BDCM and dibromochloromethane (DBCM). "
01/01/2022 - "And bromodichloromethane had the highest impact to cancer (69%), followed by chlorodibromomethane (28%). "
04/15/2019 - "In WTPs with raw water from water systems WS1, WS3, WS4, and WS5, dibromochloromethane (DBCM) in THMs has the highest contribution to cancer risk, while chloroform in THMs has the highest contribution to non-cancer risk. "
02/08/2018 - "For bromodichloromethane and dibromochloromethane, not only did their concentrations exceed the standard limits of GB 5749-2006 (60 μg·L-1 for bromodichloromethane and 100 μg·L-1 for dibromochloromethane), but their lifetime cancer risks (LCR) were estimated at unacceptable levels (>10-4). "
12/01/1985 - "Chlorodibromomethane, like chloroform, is toxic to liver and kidneys, and like chloroform induces hepatocellular tumors in mice."

08/01/1985 - "An audit of the experimental data was conducted for the 2-year toxicology and carcinogenesis studies of chlorodibromomethane. "
08/01/1985 - "NTP Toxicology and Carcinogenesis Studies of Chlorodibromomethane (CAS No. 124-48-1) in F344/N Rats and B6C3F1 Mice (Gavage Studies)."
08/01/1985 - "Toxicology and carcinogenesis studies of chlorodibromomethane (greater than 98% pure), a trihalomethane formed after chlorination of water supplies, were conducted by administering this test chemical in corn oil gavage five times per week for 104 weeks to groups of 50 male and 50 female F344/N rats at 0,40, or 80 mg/kg per day and to groups of 50 male and 50 female B6C3F1 mice for 105 weeks at doses of 0, 50, or 100 mg/kg per day. "

02/17/2004 - "The purpose of this study was to examine the ability of the THMs, trichloromethane (TCM), bromodichloromethane (BDCM), dibromochloromethane (DBCM), and tribromomethane (TBM), to induce DNA strand breaks (SB) in (1) CCRF-CEM human lymphoblastic leukemia cells, (2) primary rat hepatocytes (PRH) exposed in vitro, and (3) rats exposed by gavage or drinking water. "

10/01/1990 - "The mutagenic effects of the trihalomethanes (THMs: chloroform, CHCl3; dichlorobromomethane, CHCl2Br; dibromochloromethane, CHClBr2; bromoform, CHBr3), found in chlorinated drinking water have been studied for their ability to induce chromosome aberrations (CA) in vivo in rat bone marrow cells. "
08/12/1996 - "Six of nine chemicals induced chromosomal aberrations; bromodichloromethane, chlorendic acid and isophorone induced structural aberrations, and chlorodibromomethane, pentachloroethane and 1,1,1,2-tetrachloroethane induced numerical aberrations (polyploidy). "

01/01/1997 - "Cardiotoxicity of chlorodibromomethane and trichloromethane in rats and isolated rat cardiac myocytes."