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methylphosphonic acid (methylphosphonate)

Also Known As:

methylphosphonate; aluminum methylphosphonate; dihydrogen methylphosphonate

Networked: 20 relevant articles (2 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Organophosphorus Compounds: 300
  - methylphosphonic acid: 20

Experts

1.	Casella, Luigi: 1 article (07/2019)
2.	Dell'Acqua, Simone: 1 article (07/2019)
3.	Elbaz, Lior: 1 article (07/2019)
4.	Fischer, Bilha: 1 article (07/2019)
5.	Jantz, Thomas: 1 article (07/2019)
6.	Levy, Naomi: 1 article (07/2019)
7.	Lo Presti, Eliana: 1 article (07/2019)
8.	Nassir, Molhm: 1 article (07/2019)
9.	Pariente Cohen, Natalie: 1 article (07/2019)
10.	Shimon, Linda J W: 1 article (07/2019)

Related Diseases

1.	Pain (Aches) 02/01/2006 - "13- and 14-membered macrocyclic ligands containing methylcarboxylate or methylphosphonate pendant arms: chemical and biological evaluation of their (153)Sm and (166)Ho complexes as potential agents for therapy or bone pain palliation." 09/01/1986 - "In the search for improved lipophilic centrally active acetylcholinesterase (AChE) antidotes, a series of alpha-keto thiohydroximates were prepared and evaluated for their ability to reactivate AChEs inhibited by ethyl p-nitrophenyl methylphosphonate (EPMP) and soman (GD). "
2.	Acquired Immunodeficiency Syndrome (AIDS) 10/01/1988 - "Methylphosphonate-linked oligomers are more stable to nuclease degradation and hence could be potentially useful in the treatment of acquired immunodeficiency syndrome."
3.	Starvation 11/01/2009 - "Phosphate (Pi) starvation effect on the cytosolic Pi concentration and Pi exchanges across the tonoplast in plant cells: an in vivo 31P-nuclear magnetic resonance study using methylphosphonate as a Pi analog."
4.	BCR-ABL Positive Chronic Myelogenous Leukemia (Chronic Myelogenous Leukemia) 07/15/1994 - "Liposomal delivery of methylphosphonate antisense oligodeoxynucleotides in chronic myelogenous leukemia." 03/01/1996 - "We have previously demonstrated that liposome-incorporated methylphosphonate antisense oligodeoxynucleotides (oligos) specific for BCR-ABL can selectively inhibit the expression of p210Bcr-Abl protein and the proliferation of chronic myelogenous leukemia cells in vitro. " 09/01/1992 - "Using this approach, we have prepared a number of psoralen-methylphosphonate-oligonucleotide conjugates which are complementary to the chimeric bcr/abl mRNA associated with chronic myelogenous leukemia. "
5.	Infections 01/01/1991 - "Induction of chronic human immunodeficiency virus infection is blocked in vitro by a methylphosphonate oligodeoxynucleoside targeted to a U3 enhancer element." 10/01/1989 - "The ability of poly(L-lysine)-conjugated and methylphosphonate-modified synthetic human immunodeficiency virus type 1 (HIV-1) antisense oligodeoxyribonucleotides to protect susceptible host cells from the cytopathic effects of HIV-1 infection was studied. " 05/01/1986 - "Treatment of HSV-1-infected cells with the oligo(nucleoside methylphosphonate) d(TpCCTCCTG) (deoxynucleoside methylphosphonate residues in italic), which is complementary to the acceptor splice junction of HSV-1 IE pre-mRNA 4 and 5, before (1-24 hr) or at the time of infection caused a dose-dependent inhibition in virus replication. "

Related Drugs and Biologics

1.	Soman
2.	ethyl 4-nitrophenyl methylphosphonate
3.	Acetylcholinesterase
4.	Phosphates (Orthophosphate)
5.	Oligodeoxyribonucleotides
6.	Oligonucleotides
7.	Ligands
8.	DNA (Deoxyribonucleic Acid)
9.	Antisense Oligodeoxyribonucleotides
10.	Tyrosine (L-Tyrosine)

Related Therapies and Procedures

1.	Therapeutics