head activator peptide

undecapeptide from hydra which acts as head inducing morphogen; also isolated from sea anemone, mammalian brain & intestine

Also Known As:

HHAP; hydra growth activator; hydra head activator peptide; pGlu-Pro-Pro-Gly-Gly-Ser-Lys-Val-Ile-Leu-Phe; peptide head activator; peptide hydra morphogen; pyroglutamyl-prolyl-prolyl-glycyl-glycyl-seryl-lysyl-valyl-isoleucyl-leucyl-phenylalanine

Networked: 9 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Boeckmann, Melanie: 1 article (11/2022)
2.	Kendrovski, Vladimir: 1 article (11/2022)
3.	Martinez, Gerardo Sanchez: 1 article (11/2022)
4.	Salazar, Miguel Antonio: 1 article (11/2022)
5.	de'Donato, Francesca: 1 article (11/2022)
6.	Bafana, Adarsh: 1 article (09/2018)
7.	Dahoumane, Si Amar: 1 article (09/2018)
8.	Haselbach, Liv: 1 article (09/2018)
9.	Jeffryes, Clayton S: 1 article (09/2018)
10.	Kumar, Shishir V: 1 article (09/2018)

Related Diseases

1.	Uterine Cervical Neoplasms (Cancer of the Cervix) 06/01/2014 - "The purposes of this study were to evaluate the Hmong Health Awareness Project (HHAP), a program designed to create awareness and acceptance of breast and cervical cancer screening, and to examine participants' perceptions of the utility of the content of the workshops. "
2.	Neoplasms (Cancer) 09/15/2018 - "The results indicate that the impacts are predominantly on acidification (AP), human health particulate air (HHAP) and human toxicity non-cancer (HTNCP) potentials. " 03/01/1990 - "High performance liquid chromatography (HPLC) of extracts of hypothalamus and tumors revealed two major peaks of IR-HHAP; one eluted with the same elution volume as synthetic HHAP. " 03/01/1990 - "The concentration of IR-HHAP in the brain tumors, including the actively growing tumor front, is lower than in normal brain, and thus appears not to act as a growth factor. "
3.	Cardiomegaly (Heart Hypertrophy) 09/01/1993 - "[The dynamic changes in the tissue components of the myocardial layers under compensatory heart hypertrophy in exposure to a peptide hydra morphogen]." 03/01/1993 - "[Effect of peptide hydra morphogen on the structure of tissue components of rat myocardial layers in the early period of heart hypertrophy development]."
4.	Neuroblastoma 07/24/1992 - "The synthetic undecameric peptide, pGlu-Pro-Pro-Gly-Gly-Ser-Lys-Val-Ile-Leu-Phe, known as the hydra head activator peptide, present in high concentrations in mammalian hypothalamus and intestine, was tested for neurotrophic activity in a survival assay using cultured chick embryonic sympathetic and dorsal root ganglion cells, and for morphological differentiation activity on neuroblastoma cells. "
5.	Meningitis 01/01/1990 - "The content of peptide hydra morphogen (PHM) was measured for the first time in blood plasma and CSF by RIA in patients with purulent meningitides. " 01/01/1990 - "[The dynamics of the peptide hydra morphogen in meningitis]."

Related Drugs and Biologics

1.	head activator peptide
2.	Intercellular Signaling Peptides and Proteins (Growth Factors)
3.	Messenger RNA (mRNA)
4.	Proteins (Proteins, Gene)
5.	Peptides (Polypeptides)