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indazole-3-carboxylic acid

derivatives of above cpd are often antispermatogenic agents

Networked: 6 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- 1-Ring Heterocyclic Compounds
  - Azoles: 2138
    - Pyrazoles: 61
      - Indazoles: 179
        indazole-3-carboxylic acid: 6
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Indazoles: 179
      - indazole-3-carboxylic acid: 6

Experts

1.	Cepeda, Javier: 1 article (01/2021)
2.	Choquesillo-Lazarte, Duane: 1 article (01/2021)
3.	Fernández, Belén: 1 article (01/2021)
4.	García-García, Amalia: 1 article (01/2021)
5.	García-Valdivia, Antonio A: 1 article (01/2021)
6.	Jannus, Fatin: 1 article (01/2021)
7.	Lupiáñez, José A: 1 article (01/2021)
8.	Medina-O'donnell, Marta: 1 article (01/2021)
9.	Reyes-Zurita, Fernando J: 1 article (01/2021)
10.	Rodríguez-Diéguez, Antonio: 1 article (01/2021)

Related Diseases

1.	Neoplasms (Cancer) 03/01/1994 - "The action of Lonidamine (LND), a dichlorinated derivative of indazole-3-carboxylic acid, on the membrane and cytoskeleton of Ehrlich tumor cells was investigated. " 01/01/1989 - "Lonidamine, a dichlorinated derivative of indazole-3-carboxylic acid, has recently been indicated as an antiproliferative agent being able to reduce mitotic activity of tumor cells. " 02/21/2013 - "Two hybrid compounds comprising an antimetastatic ruthenium-arene fragment tethered to an indazole-3-carboxylic acid derivative that inhibits aerobic glycolysis in cancer cells have been prepared and evaluated in a variety of cancer cell lines, including highly relevant human glioblastoma cells, with an apparent synergistic action between the two components observed." 01/01/2021 - "Anti-cancer and anti-inflammatory activities of a new family of coordination compounds based on divalent transition metal ions and indazole-3-carboxylic acid."
2.	Acute Promyelocytic Leukemia 04/01/2003 - "Mitochondria is also a target for arsenite trioxide, an old cytotoxic agent recently used for treating acute promyelocytic leukemia, lonidamine, a dichlorinated derivative of indazole-3-carboxylic acid developped as a chemosensitizer, the retinoic acid receptor gamma activator CD437 and nitric oxide (NO). "
3.	Glioblastoma (Glioblastoma Multiforme) 02/21/2013 - "Two hybrid compounds comprising an antimetastatic ruthenium-arene fragment tethered to an indazole-3-carboxylic acid derivative that inhibits aerobic glycolysis in cancer cells have been prepared and evaluated in a variety of cancer cell lines, including highly relevant human glioblastoma cells, with an apparent synergistic action between the two components observed."
4.	Hyperthermia 11/15/1988 - "Lonidamine is a dechlorinated derivative of indazole-3-carboxylic acid which preclinically synergizes with hyperthermia. "

Related Drugs and Biologics

1.	lonidamine
2.	Ruthenium
3.	Nitric Oxide (Nitrogen Monoxide)
4.	Metals
5.	Ions
6.	Cytotoxins (Cytolysins)
7.	Retinoic Acid Receptor gamma
8.	arsenite