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3,15,17-trihydroxypregnan-20-one
found in urine of newborn infants
Also Known As:
3 alpha,15 beta,17 alpha-trihydroxy-5 beta-pregnan-20-one; 3,15,17-TH-5P; 3,15,17-trihydoxy-5alpha-pregnan-20-one; Pregnan-20-one, 3,15,17-trihydroxy-, (3alpha,5beta,15beta)-
Networked:
3
relevant articles (
0
outcomes,
0
trials/studies)
Bio-Agent Context: Research Results
Polycyclic Compounds: 6
Fused-Ring Compounds
Steroids: 70059
Pregnanes: 9
Pregnanetriol: 74
3,15,17-trihydroxypregnan-20-one: 3
Hormones, Hormone Substitutes, and Hormone Antagonists
Hormones: 80400
Gonadal Hormones: 716
Gonadal Steroid Hormones: 7657
Progesterone Congeners: 320
Progesterone: 12723
Hydroxyprogesterones
17-alpha-Hydroxyprogesterone: 804
Pregnanetriol: 74
3,15,17-trihydroxypregnan-20-one: 3
Related Diseases
1.
Congenital Adrenal Hyperplasia (Hyperplasia, Congenital Adrenal)
02/01/1996 - "
In an attempt to develop a new and reliable immunoassay method for use in newborn screening programs for congenital adrenal hyperplasia, we report the chemical synthesis of 3 alpha,15 beta,17 alpha-trihydroxy-5 beta-pregnan-20-one (2) from 3 alpha-hydroxy-5 beta-androstan-17-one (4) in 9 steps.
"
12/01/1995 - "
In recent years several 15 beta-hydroxysteroids have emerged pathognomonic of adrenal disorders in human neonates of which 3 alpha,15 beta,17 alpha-trihydroxy-5 beta-pregnan-20-one (2) was the first to be identified in the urine of newborn infants affected with congenital adrenal hyperplasia.
"
09/01/1981 - "
Identification of 15 beta-hydroxylated C21 steroids in the neo-natal period: the role of 3 alpha,15 beta,17 alpha-trihydroxy-5 beta-pregnan-20-one in the perinatal diagnosis of congenital adrenal hyperplasia (CAH) due to a 21-hydroxylase deficiency.
"
2.
Congenital adrenal hyperplasia due to 21 hydroxylase deficiency
09/01/1981 - "
Identification of 15 beta-hydroxylated C21 steroids in the neo-natal period: the role of 3 alpha,15 beta,17 alpha-trihydroxy-5 beta-pregnan-20-one in the perinatal diagnosis of congenital adrenal hyperplasia (CAH) due to a 21-hydroxylase deficiency.
"
Related Drugs and Biologics
1.
Steroids
2.
Hydroxysteroids
3.
compound 21