Aclarubicin

An anthracycline produced by Streptomyces galilaeus. It has potent antineoplastic activity.

Also Known As:

Aclacin; Aclaplastin; MA-144A1; NSC-208734; MA 144A1; MA144A1; NSC 208734; NSC208734; Aclacinomycin A; 1-Naphthacenecarboxylic acid,(2- ethyl- 1,2,3,4,6,11- hexahydro- 2,5,7- trihydroxy- 6,11- dioxo- 4- ((2,3,6- trideoxy- 4- O- (2,6- dideoxy- 4- O- ((2R- trans)- tetrahydro- 6- methyl- 5- oxo- 2H- pyran- 2- yl)- alpha- L- lyxo- hexopyranosyl)- 3- (dimethylamino)- alpha- L- lyxo- hexopyranosyl)- 3- (dimethylamino)- alpha- L- lyxo- hexopyranosyl)oxy)- , methyl ester, (1R-(1alpha,2beta,4beta))-

Pharmalogical Action Categories:

Antibiotics, Antineoplastic
Topoisomerase II Inhibitors

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Cyclic Hydrocarbons: 97
    - Aromatic Hydrocarbons: 291
      - Polycyclic Aromatic Hydrocarbons: 2020
        Naphthacenes
        Anthracyclines: 9423
        Aclarubicin: 368
Polycyclic Compounds: 6
- Polycyclic Aromatic Hydrocarbons: 2020
  - Naphthacenes
    - Anthracyclines: 9423
      - Aclarubicin: 368
Carbohydrates: 22023
- Glycosides: 2119
  - Aminoglycosides: 5131
    - Anthracyclines: 9423
      - Aclarubicin: 368

6-O-methylaclacinomycin

Bio-Agent Context: Research Results