Clostridium difficile toxB protein

Also Known As:

toxB protein, Clostridium difficile; CD cytotoxin B, Clostridium difficile; CD cytotoxin, Clostridium difficile; Clostridium difficile toxin B; tcdB protein, Clostridium difficile; toxin B, Clostridium difficile; toxin B-1470, Clostridium difficile

Networked: 29 relevant articles (1 outcomes, 1 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Bacterial Proteins: 394
    - Clostridium difficile toxB protein: 29
Biological Factors: 2472
- Biological Toxins: 20
  - Bacterial Toxins: 814
    - Clostridium difficile toxB protein: 29

Experts

1.	Chen, Yijian: 2 articles (12/2020 - 01/2020)
2.	Li, Ying: 2 articles (12/2020 - 01/2020)
3.	Xu, Qingqing: 2 articles (12/2020 - 01/2020)
4.	Li, Shan: 2 articles (11/2014 - 01/2014)
5.	Wang, Haiying: 2 articles (11/2014 - 01/2014)
6.	Wang, Jufang: 2 articles (11/2014 - 01/2014)
7.	Feng, Hanping: 2 articles (01/2014 - 01/2012)
8.	Chumbler, Nicole M: 2 articles (11/2013 - 01/2012)
9.	Farrow, Melissa A: 2 articles (11/2013 - 01/2012)
10.	Franklin, Jeffrey L: 2 articles (11/2013 - 01/2012)

Related Diseases

1.	Rabies (Hydrophobia) 08/08/2019 - "Moreover, DABMA exhibited enhanced efficacy against Clostridium difficile toxin B (TcdB), Clostridium sordellii lethal toxin (TcsL), Pseudomonas Exotoxin A (PE) as well as Rabies and Ebola viruses. "
2.	Fever (Fevers) 01/01/1996 - "This study investigated the ability of Clostridium difficile toxin B, isolated from the VPI 10463 strain, to induce fever and neutrophilia in rats. " 01/01/1996 - "Effects of anti-inflammatory drugs on fever and neutrophilia induced by Clostridium difficile toxin B."
3.	Diarrhea 12/01/2015 - "CDI was diagnosed by detection of Clostridium difficile toxin B gene using polymerase chain reaction-based stool assay in patients with clinically significant diarrhea within 90 days of the index operation. " 04/01/2005 - "Clostridium difficile toxin B (TxB) mediates acute inflammatory diarrhea characterized by neutrophil infiltration and intestinal mucosal injury. " 01/01/2000 - "Among the 98 patients with diarrhea, Clostridium difficile toxin B was identified in the stool of 13. " 11/07/2003 - "Clostridium difficile toxin B (269 kDa) is one of the causative agents of antibiotic-associated diarrhea and pseudomembranous colitis. " 04/06/2001 - "Clostridium difficile toxin B (269 kDa), which is one of the causative agents of antibiotic-associated diarrhea and pseudomembranous colitis, inactivates Rho GTPases by glucosylation. "
4.	Pseudomembranous Enterocolitis (Pseudomembranous Colitis) 06/01/1990 - "Clostridium difficile toxin B is a powerful cytopathic agent without enterotoxic activity which is believed to be involved in the pathogenesis of pseudomembranous colitis. " 03/01/1995 - "The principal cellular response to Clostridium difficile toxin B, a protein toxin associated with antibiotic-associated colitis, is the disassembly of actin microfilaments. " 11/07/2003 - "Clostridium difficile toxin B (269 kDa) is one of the causative agents of antibiotic-associated diarrhea and pseudomembranous colitis. " 04/06/2001 - "Clostridium difficile toxin B (269 kDa), which is one of the causative agents of antibiotic-associated diarrhea and pseudomembranous colitis, inactivates Rho GTPases by glucosylation. "
5.	Necrosis 01/01/2012 - "Clostridium difficile Toxin B causes epithelial cell necrosis through an autoprocessing-independent mechanism." 11/12/2013 - "Clostridium difficile toxin B-induced necrosis is mediated by the host epithelial cell NADPH oxidase complex." 06/01/1997 - "The involvement of macrophage-derived tumour necrosis factor and lipoxygenase products on the neutrophil recruitment induced by Clostridium difficile toxin B."

Related Drugs and Biologics

1.	Exotoxins
2.	Clostridium sordellii lethal toxin LT
3.	trimethylaminocarboxyldihydroboran (TCDB)
4.	4-dimethylaminoazobenzene-4'-N-maleimide
5.	IgE Receptors (Fc epsilon RI)
6.	Proteins (Proteins, Gene)
7.	Anti-Bacterial Agents (Antibiotics)
8.	rho GTP-Binding Proteins (rho GTP-Binding Protein)
9.	GTP Phosphohydrolases (GTPases)
10.	Phosphatidylinositol 3-Kinases (PI 3 Kinase)