stubomycin (hitachimycin)

contains polyene amide group; from Streptomyces

Also Known As:

hitachimycin; Cyclopent(i)azacyclononadecine-7,17(8H,19H)-dione, 9,10,13,14,15,16,20,20a-octahydro-15,18-dihydroxy-19-methoxy-2-methyl-9-phenyl-

Networked: 5 relevant articles (2 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Hydrocarbons: 1713
  - Acyclic Hydrocarbons
    - Alkenes: 265
      - Polyenes: 164
        stubomycin: 5

Related Diseases

1.	Carcinoma (Carcinomatosis) 06/01/1982 - "with IMC-carcinoma were cured when they were given nine successive injections of stubomycin. " 06/01/1982 - "Stubomycin showed antitumor activity against Sarcoma 180, IMC-carcinoma and Meth-A tumor. " 04/01/1983 - "Stubomycin, discovered by Dr. Umezawa, Kitasato Institute, is effective against Sarcoma 180, Ehrlich carcinoma, P388 leukemia, IMC carcinoma and Meth-A tumor in mice, and shows low acute toxicity. " 06/01/1982 - "Stubomycin also showed remarkable antitumor effects against Sarcoma 180 and Ehrlich ascites carcinoma when administered concomitantly with bleomycin."
2.	Sarcoma 180 07/01/1989 - "Amino acyl derivatives of hitachimycin have been synthesized and evaluated their activities including antibacterial, cytocidal against HeLa cells and in vivo antitumor against sarcoma 180. " 05/01/1988 - "Several acyl derivatives of hitachimycin have been synthesized and their activities, including antibacterial, cytocidal against HeLa cells and in vivo antitumor against sarcoma 180, evaluated. " 05/01/1989 - "Several carbonate derivatives of hitachimycin have been synthesized and evaluated their activities including antibacterial, cytocidal against HeLa cells and in vivo antitumor against Sarcoma 180. " 06/01/1982 - "Stubomycin showed antitumor activity against Sarcoma 180, IMC-carcinoma and Meth-A tumor. " 04/01/1983 - "Stubomycin, discovered by Dr. Umezawa, Kitasato Institute, is effective against Sarcoma 180, Ehrlich carcinoma, P388 leukemia, IMC carcinoma and Meth-A tumor in mice, and shows low acute toxicity. "
3.	Neoplasms (Cancer) 06/01/1982 - "The antitumor activity of a new antibiotic, stubomycin, against various murine tumors was studied. " 06/01/1982 - "Stubomycin showed antitumor activity against Sarcoma 180, IMC-carcinoma and Meth-A tumor. " 04/01/1983 - "Stubomycin, discovered by Dr. Umezawa, Kitasato Institute, is effective against Sarcoma 180, Ehrlich carcinoma, P388 leukemia, IMC carcinoma and Meth-A tumor in mice, and shows low acute toxicity. "
4.	Leukemia P388 04/01/1983 - "Stubomycin, discovered by Dr. Umezawa, Kitasato Institute, is effective against Sarcoma 180, Ehrlich carcinoma, P388 leukemia, IMC carcinoma and Meth-A tumor in mice, and shows low acute toxicity. "
5.	Ascites 06/01/1982 - "Stubomycin also showed remarkable antitumor effects against Sarcoma 180 and Ehrlich ascites carcinoma when administered concomitantly with bleomycin."

Related Drugs and Biologics

1.	Carbonates
2.	Bleomycin (Blenoxane)
3.	Anti-Bacterial Agents (Antibiotics)

Related Therapies and Procedures

1.	Injections