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growth inhibitory proteins

membrane protein which arrests cell growth in the 3T3 cell plasma membrane; see also record for FIBROBLAST GROWTH FACTOR; do not use /antag

Networked: 17 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Membrane Proteins: 10078
    - growth inhibitory proteins: 17

Experts

1.	Brazda, Nicole: 1 article (01/2015)
2.	Estrada, Veronica: 1 article (01/2015)
3.	Faissner, Andreas: 1 article (01/2015)
4.	Krafft, Stefanie: 1 article (01/2015)
5.	König, Brigitte: 1 article (01/2015)
6.	McKerracher, Lisa: 1 article (01/2015)
7.	Müller, Hans Werner: 1 article (01/2015)
8.	Rosen, Kenneth M: 1 article (01/2015)
9.	Vogelaar, Christina Francisca: 1 article (01/2015)
10.	Ziegler, Brigida: 1 article (01/2015)

Related Diseases

1.	Deafness (Deaf Mutism) 02/01/2002 - "The results achieved in this study were consistent with the following conclusions: 1) transection of the adult rat cochlear nerve at the CPA results in functional deafness, disappearance of BAEP, apoptosis of parent axotomized neurons of the spiral ganglion, and interruption of labelled axons close to the lesion site; 2) NT-3 is able to partially rescue axotomized neurons of the spiral ganglion; 3) injured cochlear nerve fibres show a limited spontaneous sprouting and regrowth response which does not lead to BAEP recovery; 4) intrathecal treatment with IN-1 directed against myelin-associated neurite growth inhibitory proteins promotes significant elongation of the injured fibres; and 5) the regenerating fibres seem to navigate to correct targets, and be able to establish synaptic connections for functional recovery as depicted by BAEP examinations."
2.	Neoplasms (Cancer) 02/11/2005 - "Genes encoding growth-inhibitory proteins are postulated to be candidate tumor suppressors. " 11/01/2004 - "Further investigations of these factors may result in the identification of autocrine/paracrine tumor cell growth inhibitory proteins for future use in clinical applications." 01/01/2003 - "Retinoid-induced tumor suppression is associated with the induction of multiple intracellular and secreted growth-inhibitory proteins. " 03/15/2011 - "Noscapine (300 mg/kg), Doxorubicin (1.5 mg/kg) and combination treatment reduced tumor volume by 39.4±5.8, 34.2±5.7 and 82.9±4.5 percent respectively and showed decreased expression of NF-KB pathway proteins, VEGF, cell survival, and increased expression of apoptotic and growth inhibitory proteins compared to single-agent treatment and control groups. "
3.	Stroke (Strokes) 09/01/2007 - "Neurite growth inhibitory proteins such as Nogo-A play a critical role in impeding regain of function after stroke. " 06/01/2005 - "These results identify a unique profile of growth-promoting gene expression in adult cortex after stroke, the inhibitory molecules that are present during the sprouting response, and a region in which growth-promoting genes are increased, growth-inhibitory proteins are diminished and axonal sprouting occurs. "
4.	Retinoblastoma (Glioblastoma, Retinal) 06/07/1996 - "Cell cycle regulation by the retinoblastoma family of growth inhibitory proteins." 10/18/1996 - "Transformation by E1A is mediated at least in part through binding to several cellular proteins, including the three members of the retinoblastoma family of growth inhibitory proteins. " 06/07/1996 - "The retinoblastoma family of growth-inhibitory proteins act by binding and inhibiting several proteins with growth-stimulatory activity, the most prominent of which is the cellular transcription factor E2F. "
5.	Gliosis 03/31/2010 - "A major barrier to regeneration of CNS axons is the presence of growth-inhibitory proteins associated with myelin and the glial scar. " 06/01/2009 - "The regenerative processes are blocked by diverse factors such as growth inhibitory proteins and the glial scar formed in the site of lesion. "

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	E2F Transcription Factors
3.	Mutant Proteins (Protein, Mutant)
4.	Metalloproteases (Metalloproteinases)
5.	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)
6.	NF-kappa B (NF-kB)
7.	Oncogene Proteins (Oncogene Protein)
8.	Retinoids
9.	Peptides (Polypeptides)
10.	Noscapine (Narcotine)