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nitrogen trioxide (dinitrogen trioxide)

Also Known As:

dinitrogen trioxide; nitrous anhydride

Networked: 4 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Inorganic Chemicals: 9

Experts

1.	Barbee, Kenneth A: 1 article (11/2016)
2.	Buerk, Donald G: 1 article (11/2016)
3.	Jaron, Dov: 1 article (11/2016)
4.	Liu, Yien: 1 article (11/2016)
5.	Ali, Ahlam A: 1 article (03/2013)
6.	Coulter, Jonathan A: 1 article (03/2013)
7.	Hirst, David G: 1 article (03/2013)
8.	McCarthy, Helen O: 1 article (03/2013)
9.	Migaud, Marie M: 1 article (03/2013)
10.	Ogle, Claire H: 1 article (03/2013)

Related Diseases

1.	Hypoxia (Hypoxemia) 03/28/2013 - "Fluorimetric analysis in the presence of scavengers suggest for the first time that another RNS, dinitrogen trioxide may be responsible for the cytotoxicity with DETA/NO. Results showed destabilization of HIF (hypoxia inducible factor)-1α and depletion of GSH levels following the treatment with DETA/NO under hypoxia, which renders cells more susceptible to DETA/NO cytotoxicity, and could account for another mechanism of DETA/NO cytotoxicity under hypoxia. " 11/30/2016 - "We developed a mathematical model for an arteriole and surrounding tissue to examine the hypothesis that dinitrogen trioxide (N2O3) acts as a stable intermediate for preserving NO. Our simulations predict that with hypoxia and moderate nitrite concentrations, the N2O3 pathway can significantly preserve the NO produced by hemoglobin nitrite reductase in the erythrocyte and elevate NO reaching the smooth muscle cells. "
2.	Necrosis 08/01/2001 - "High NO concentrations lead to the formation of toxic reaction products like dinitrogen trioxide or peroxynitrite that induce cell death, if not by apoptosis, then by necrosis. "
3.	Inflammation (Inflammations) 09/01/2008 - "A critical link between inflammation and disease may lie in the secretion of highly reactive oxygen and nitrogen species by macrophages and neutrophils, including hypohalous acids, nitrous anhydride, and nitrosoperoxycarbonate. "

Related Drugs and Biologics

1.	Peroxynitrous Acid (Peroxynitrite)
2.	Oxygen (Dioxygen)
3.	Nitrogen
4.	Nitrites
5.	Nitrite Reductases (Nitrite Reductase)
6.	Hemoglobins (Hemoglobin)
7.	Acids
8.	nitrosoperoxycarbonate
9.	1- hydroxy- 2- oxo- 3,3- bis(2- aminoethyl)- 1- triazene