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17- N,N- diethylcarbamoyl- 4- methyl- 4- azaandrostane- 3- one (DMAA)

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inhibitor of testosterone 5-alpha reductase, receptor binding & nuclear uptake of androgens in the prostate

Also Known As:

DMAA; 17 beta-N,N-diethylcarbamoyl-4-methyl-4-aza-5 alpha-androstan-3-one; 17-N,N-diethyl-4-methyl-3-oxo-4-azaandrostane-17-carboxamide; 4MA compound; 4-Azaandrostane-17-carboxamide, N,N-diethyl-4-methyl-3-oxo-, (5alpha,17beta)-

Networked: 75 relevant articles (8 outcomes, 7 trials/studies)

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Bio-Agent Context: Research Results

Experts

1.	Coughlin, Michael J: 3 articles (04/2014 - 05/2013)
2.	Nery, Caio: 3 articles (05/2013 - 09/2002)
3.	Sherriff, F: 3 articles (01/2004 - 01/2003)
4.	Lee, Kyung Tai: 2 articles (12/2014 - 08/2013)
5.	Park, Young Uk: 2 articles (12/2014 - 08/2013)
6.	Young, Ki Won: 2 articles (12/2014 - 08/2013)
7.	Kim, Jin Su: 2 articles (12/2014 - 08/2013)
8.	Ballerini, Flávio José: 2 articles (05/2013 - 05/2013)
9.	Baumfeld, Daniel: 2 articles (05/2013 - 05/2013)
10.	Kobata, Silvia: 2 articles (05/2013 - 05/2013)

Related Diseases

1.	Hallux Valgus (Bunion) 04/01/2015 - "There was a statistically significant improvement in the inter-metatarsal angle (IMA, p = 0.0003), hallux valgus angle (HVA, p < 0.0001) and distal metatarsal articular angle (DMAA, p = 0.019). " 01/01/2008 - "Radiological assessment revealed a significant improvement (p<0.001) of the hallux valgus angle (mean reduction 17.4 degrees), the intermetatarsal angle (mean reduction 5.8 degrees), the medial sesamoid position (14% of the feet were grade 1 or less preoperatively and this rate increased to 84% at follow-up) and the DMAA (mean reduction 9 degrees). " 08/01/2012 - "Hallux valgus angle (HVA), IMA and DMAA corrections improved with the formula (p = 0.036, p = 0.049, and p = 0.006, respectively). " 12/01/2009 - "The mean hallux valgus angle improved from 28 degrees pre-op to 14 degrees post-op, the intermetatarsal angle from 12 degrees to 7 degrees and the DMAA from 20 degrees to 7 degrees. " 09/01/2002 - "The hallux valgus angle was improved from an average of 25 degrees to 14 degrees, the first intermetatarsal angle from 12 degrees to 8 degrees and the DMAA from 15 degrees to 5 degrees. "
2.	Congenital Abnormalities (Deformity) 07/01/2015 - "Recurrence was associated with greater preoperative deformity and an increased preoperative DMAA. " 05/01/2013 - "The algorithm was based mainly upon the presence of increased DMAA and increased severity of angular deformities. " 01/01/2013 - "However, the measurement of DMAA is expected to be dependent on the rotational deformity of the hallux." 08/01/2012 - "The formula allows precise, reproducible, anatomical correction of IMA and DMAA deformities. " 01/01/2008 - "IMA and DMAA were not significant for prediction of postoperative HVA in logistic regression, although they were significantly increased in larger deformities. "
3.	Dementia (Dementias) 01/01/2004 - "Trials were identified from a search of the Trial-based Specialized Register of the Cochrane Dementia and Cognitive Improvement Group on 7 April 2004 using the terms: memantin, namenda, ebixa, axura, D-145, DMAA, DRG-0267. " 01/01/2003 - "Trials were identified from a search of the Specialized Register of the Cochrane Dementia and Cognitive Improvement Group on 15 April 2003 using the terms: memantin, D-145, DMAA, DRG-0267. " 01/01/2003 - "Trials were identified from a search of the Trial-based Specialized Register of the Cochrane Dementia and Cognitive Improvement Group on 9 October 2002 using the terms: memantin, D-145, DMAA, DRG-0267. "
4.	AIDS-Related Complex (ARC) 02/01/2007 - "The objectives of this study were to determine the center of the circle formed by the first metatarsophalangeal arc circumference and to correlate the location of the center with the hallux valgus angle (HVA), the intermetatarsal angle (IMA), the distal metatarsal articular angle (DMAA), and the proximal phalangeal articular angle (PPAA) measurements. "
5.	Weight Loss (Weight Reduction) 07/01/2014 - "Dimethylamylamine (DMAA) is a sympathomimetic amine found in weight-loss/workout supplements or used as an appetite suppressant. " 01/01/2013 - "1,3-Dimethylamylamine (DMAA) is an ingredient in a number of weight loss and exercise performance enhancing products. " 10/01/2012 - "DMAA has recently gained popularity as a dietary supplement, with claims of effectiveness as an athletic performance enhancer and weight loss aid. "

Related Drugs and Biologics

1.	Memantine (Namenda)
2.	polyterephthalic acid anhydride
3.	Cacodylic Acid (Cacodylate)
4.	Arsenic
5.	Cholestenone 5 alpha-Reductase (5 alpha-Reductase)
6.	9,10-Dimethyl-1,2-benzanthracene (DMBA)
7.	Valproic Acid (Valproate, Semisodium)
8.	Sodium
9.	Phenytoin (Dilantin)
10.	Metallothionein

Related Therapies and Procedures

1.	Osteotomy
2.	Transplants (Transplant)
3.	Communication Aids for Disabled (TDD)