imperatorin

08/01/1997 - "At dose levels higher than those effective against DMBA, imperatorin also inhibited tumor initiation by B[a]P. "
11/12/2023 - "This study investigates the chemosensitizing potential of imperatorin in ABCG2-overexpressing cancer cells. "
05/05/2017 - "The aim of this study was to investigate the effectiveness of imperatorin as a treatment of cancer and to identify the underlying mechanisms of its anticancer activity. "
11/12/2023 - "Imperatorin Restores Chemosensitivity of Multidrug-Resistant Cancer Cells by Antagonizing ABCG2-Mediated Drug Transport."
12/19/2021 - "Imperatorin triggered time-dependent and dose-dependent inhibition of tumor growth mainly by inducing autophagy promotion and G0/G1 phase arrest in vitro and in vivo. "

08/30/2022 - "Here, we investigated the effects and mechanisms of imperatorin (IPT) on proliferation, migration, and inflammation in primary cultured arthritic FLSs. "
08/30/2022 - "Imperatorin Inhibits Proliferation, Migration, and Inflammation via Blocking the NF-κB and MAPK Pathways in Rheumatoid Fibroblast-like Synoviocytes."
06/01/2017 - "Taken together, imperatorin can blunt inflammation by inhibiting the ROS-mediated activation of the PI3K/Akt/NF-κB pathway."
12/01/2012 - "Imperatorin attenuates LPS-induced inflammation by suppressing NF-κB and MAPKs activation in RAW 264.7 macrophages."
01/01/2019 - "In this study, we examined the anti-inflammatory effects of imperatorin on inflammation-associated lung diseases. "

01/01/2016 - "Imperatorin may possess therapeutic potential against Th2-mediated allergic asthma not only via stimulating DC induction of Tregs but also via direct inhibition of Th2 cell activation. "
10/18/2022 - "In this study, we investigated whether imperatorin has protective effects against Dermatophagoides pteronyssinus (Der p)-induced asthma in mice. "
10/18/2022 - "These findings suggest that imperatorin has a considerable anti-inflammatory effect on Der p-induced allergic asthma in mice."
10/18/2022 - "Ameliorative Effect of Imperatorin on Dermatophagoides pteronyssinus-Induced Allergic Asthma by Suppressing the Th2 Response in Mice."
01/01/2016 - "These findings provide new insights into how imperatorin affects the Th2 immune response and the development of imperatorin as a Treg-type immunomodulatory agent to treat allergic asthma."

09/01/2020 - "Imperatorin ameliorates learning and memory deficits through BDNF/TrkB and ERK/CaMKIIα/CREB signaling in prenatally-stressed female offspring."
10/01/2018 - "Imperatorin ameliorates lipopolysaccharide induced memory deficit by mitigating proinflammatory cytokines, oxidative stress and modulating brain-derived neurotropic factor."

02/22/2012 - "Western blotting revealed that imperatorin decreased Carr-induced iNOS and COX-2 expressions at 5 h in edema paw. "
02/01/2020 - "In carrageenan-induced paw edema test, maximum possible anti-inflammatory effect of imperatorin was evident after 240 min of carrageenan administration.Conclusion"
02/01/2020 - "Carrageenan inflicted paw edema was employed to explore the anti-inflammatory activity of imperatorin.Results"
02/22/2012 - "We also demonstrated that imperatorin significantly attenuated the malondialdehyde level in the edema paw at the fifth hour after Carr injection. "
01/01/2019 - "We found that imperatorin exerts anti-inflammatory effects that are associated with amelioration of lung inflammation, edema, and rapid fibrosis. "