titanium alloy (TiAl6V4)

used for internal fixation of fractures; contains in addition to titanium, aluminum, vanadium, iron, carbon, oxygen, nitrogen & hydrogen; meets requirement of ASTM specification F136-70

Also Known As:

Networked: 208 relevant articles (8 outcomes, 42 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Experts

1.	Yang, Ke: 4 articles (01/2022 - 01/2017)
2.	Conde, Ana: 4 articles (01/2020 - 12/2017)
3.	Esteban, Jaime: 4 articles (01/2020 - 12/2017)
4.	Ren, Ling: 3 articles (01/2022 - 01/2021)
5.	Cai, Hong: 3 articles (12/2021 - 01/2018)
6.	Liu, Zhongjun: 3 articles (12/2021 - 01/2018)
7.	Zhang, Teng: 3 articles (12/2021 - 01/2018)
8.	Skelly, Jordan D: 3 articles (09/2020 - 08/2019)
9.	Song, Jie: 3 articles (09/2020 - 08/2019)
10.	Arenas, María-Ángeles: 3 articles (01/2020 - 01/2019)

Related Diseases

1.	Fatigue 05/12/2020 - "It was revealed that the fatigue strength at N = 107 of Ti6Al4V manufactured by DMLS was slightly better than that of Ti6Al4V manufactured by EBM, and the fatigue strength of both the DMLS and EBM specimens was improved by about two times through cavitation peening, compared with the as-built ones. " 01/01/2017 - "In addition, impact assembly substantially improved the fatigue life of Ti6Al4V necks and also led to overall higher distraction forces for both neck materials. " 04/01/2011 - "Fatigue endurance of Ti-6Al-4V alloy with electro-eroded surface for improved bone in-growth." 08/20/2020 - "The current study is proposing a design envelope for porous Ti-6Al-4V alloy femoral stems to survive under fatigue loads. " 02/09/2019 - "The aim of this study was to determine the influence of plasma nitriding on the fatigue behavior of a Ti-6Al-4V alloy with a lamellar microstructure (Widmanstätten type). "
2.	AIDS-Related Complex (ARC) 12/01/2019 - "Study of the Effect of Current Pulse Frequency on Ti-6Al-4V Alloy Coating Formation by Micro Arc Oxidation." 02/07/2020 - "This article discusses the analysis of the production and subsequent machining in the quality of TI6Al4V produced by Wire Arc Additive Manufacturing (WAAM), more specifically Plasma Arc Welding (PAW). " 07/04/2017 - "Effect of Molten Pool Size on Microstructure and Tensile Properties of Wire Arc Additive Manufacturing of Ti-6Al-4V Alloy." 12/01/2012 - "In this work, five types of metallic Ti-C-N coatings deposited by physical vapor deposition (PVD) cathodic arc method on Ti6Al4V substrate have been studied. " 10/01/1995 - "Casting of Ti-6Al-4V alloy compared with pure Ti in an Ar-arc casting machine."
3.	Osteosarcoma (Osteogenic Sarcoma) 12/01/2011 - "This study reports comparatively on the responses of three human osteosarcoma cell lines, MG-63, Saos-2 and U-2 OS, and human primary osteoblasts cultured on Ti6Al4V surfaces or exposed to Ti particles. " 01/01/2020 - "The biocompatibility of the bare Ti6Al4V substrate and coated surfaces was evaluated by testing the cellular adhesion and viability/proliferation of human osteosarcoma cells (MG-63) after 72 h of incubation. " 09/01/2021 - "The recurrence of osteosarcoma (OS) after reconstruction using Ti6Al4V prostheses remains a major problem in the surgical treatment of OS. " 01/01/2020 - "This study further shows that porous TiTa scaffolds fabricated using L-PBF are biocompatible with comparable biological results and manufacturability as Ti6Al4V and commercially pure titanium, based on the results obtained from cell culture with human osteosarcoma cell line SAOS-2." 09/01/2021 - "Biofunctional magnesium-coated Ti6Al4V scaffolds promote autophagy-dependent apoptosis in osteosarcoma by activating the AMPK/mTOR/ULK1 signaling pathway."
4.	Neoplasms (Cancer) 10/01/2021 - "Ti6Al4V is widely used in metastatic spine tumor surgery (MSTS) and is the current implant material of choice due to improved biocompatibility, mechanical properties, and compatibility with imaging modalities compared to stainless steel. " 01/01/2022 - "This study compared the biomechanical performance of porous Ti6Al4V block and tumor prosthesis UHMWPE block in treating distal femoral bone defects. " 01/01/2022 - "Biomechanical Comparison Between Porous Ti6Al4V Block and Tumor Prosthesis UHMWPE Block for the Treatment of Distal Femur Bone Defects." 01/01/2022 - "Titanium and titanium alloys (Ti6Al4V and Ti) have been widely used in bone tissue engineering to repair maxillofacial bone defects caused by traumas and tumors. "
5.	Infections 12/01/2019 - "Additional studies are needed to determine whether an SLM porous Ti6Al4V implant increases the risk of implant-related infection in vivo. " 06/01/2019 - "This study proposes a simple and efficient method to enhance the antibacterial property of Ti6Al4V surfaces to avoid implant-related infection." 12/01/2017 - "We designed an in vitro study using Ti6Al4V discs and 5 different bacteria to determine the optimal sonication time for recovery of most bacteria tested to enable use of sonication in clinical practice for microbiological diagnosis of implant-related infections. " 06/23/2017 - "The purpose of our study was to investigate the antibacterial effect of a spacer (Ti6Al4V) coated with 4x Cu-TiO₂ in an animal model simulating an acute periprosthetic infection by Staphylococcus aureus. " 12/01/2023 - "In summary, the novel GO/Sr nanocomposite coating on the surface of Ti6Al4V effectively prevents surface colonization of Staphylococcus aureus and eliminates local infections in vitro and in vivo."

Related Drugs and Biologics

1.	Alloys
2.	Electrolytes
3.	Stainless Steel (Steel, Stainless)
4.	Hydrogels
5.	Cisplatin (Platino)
6.	Titanium
7.	Monoamine Oxidase (MAO)
8.	Magnesium
9.	Aluminum
10.	ultra-high molecular weight polyethylene (UHMWPE)

Related Therapies and Procedures

1.	Lasers (Laser)
2.	Prostheses and Implants (Prosthesis)
3.	Hip Prosthesis
4.	Bone Screws
5.	Bone Plates (Bone Plate)