diamidino compound 253/50

fluorescent retrograde neuronal tracer
Also Known As:
Fast Blue
Networked: 71 relevant articles (0 outcomes, 5 trials/studies)

Bio-Agent Context: Research Results


1. Kaleczyc, J: 2 articles (05/2002 - 11/2001)
2. Czaja, K: 2 articles (05/2002 - 11/2001)
3. Kusakabe, Tatsumi: 1 article (02/2015)
4. Takaki, Fumiya: 1 article (02/2015)
5. Yamamoto, Yoshio: 1 article (02/2015)
6. Nakamuta, Nobuaki: 1 article (02/2015)
7. Vizzard, Margaret A: 1 article (07/2013)
8. Girard, Beatrice M: 1 article (07/2013)
9. Malley, Susan E: 1 article (07/2013)
10. Arms, Lauren: 1 article (07/2013)

Related Diseases

1. Ganglion Cysts (Ganglion)
2. Inflammation
06/01/2005 - "Allergic airway inflammation was found to induce the expression of SP/NKA (13.2+/-1.43% vs. 5.8+/-0.37%, P<0.01) in large-diameter (>20 microm) vagal sensory neurons retrograde labelled with Fast blue dye from the main stem bronchi. "
11/01/2003 - "Ileitis was induced in guinea pig ileum with trinitrobenzene sulphonic acid (TBNS) and dorsal root ganglion neurons innervating the site of inflammation were identified by Fast Blue or DiI fluorescence labelling. "
09/19/1997 - "In cats with an acute (32 h) unilateral knee joint inflammation the proportion of calcitonin gene-related peptide-(CGRP) and substance P-(SP) immunoreactive articular afferents, retrogradely labelled by Fast Blue (FB), were determined using immunohistochemistry. "
02/04/2011 - "To investigate the inhibition effects of DLA on secondary injury of SCI, focusing especially on suppression of inflammatory responses and the mechanism of this effect, the following studies were performed: Basso, Beattie, and Bresnahan (BBB) scores to assess motor functions till 10 days after SCI; Nissl and Fast Blue histological staining and immunohistochemistry of inhibitory-kappa B-alpha (IκB-α) and nuclear factor-kappa B (NF-κB) p65 subunit protein; levels of myeloperoxidase (MPO) activity analysis as an indicator of polymorphonuclear infiltration; IL-6 production in plasma 10 days after SCI; Western blot analysis to determine cytoplasm levels of IκB-α and NF-κB p65 subunit proteins in the nuclear fractions 10 days after SCI. DLA significantly attenuated the motor function and tissue damage following SCI in rats, significant reduced polymorphonuclear cell infiltration and IL-6 production, as well as reduced cytoplasm IκB-α degradation and the nuclear translocation of NF-κB p65 subunit protein after SCI. In conclusion, the results clearly demonstrate that DLA inhibit the inflammation responses induced by SCI via inhibiting effect of production of IL-6 and nuclear translocation of NF-κB."
3. Spinal Cord Injuries (Spinal Cord Injury)
4. Neoplasms (Cancer)
5. Glioma (Gliomas)

Related Drugs and Biologics

1. Protein Subunits (Protein Subunit)
2. NF-kappa B (NF-kB)
3. Interleukin-6 (Interleukin 6)
4. Proteins (Proteins, Gene)
5. Peroxidase (Myeloperoxidase)
6. Horseradish Peroxidase
7. diamidino yellow
8. Nitric Oxide Synthase (NO Synthase)
9. Vasoactive Intestinal Peptide (VIP (Vasoactive Intestinal Peptide))
10. Substance P

Related Therapies and Procedures

1. Injections
2. Sympathectomy (Sympathectomies)