artemisinine (artemisinin)

04/01/2015 - "Although artemisinin combination therapies (ACTs) are the recommended first-line treatment for uncomplicated malaria in most endemic countries, they have been prohibitively expensive in the retail sector where many suspected malaria cases purchase treatment. "
01/01/2015 - "Artemisinin from Artemisia annua is still one of the most effective treatments for malaria. "
01/01/2015 - "Artemisinin combination therapy (ACT) is first-line treatment for malaria in most endemic countries and is increasingly available in the private sector. "
09/22/2014 - "Artemisinin has been increasingly popular as an effective and safe alternative therapy against malaria; also proved effective against the highly adaptable malaria parasite, which has already become resistant to many other drugs. "
10/01/2013 - "Following a decade-long scale up of malaria control through vector control interventions, the introduction of rapid diagnostic tests and highly efficacious Artemisinin-based Combination Therapy (ACT) along with other measures, global malaria incidence declined significantly. "

07/01/2011 - "Artemisinin-based combination therapies (ACTs) are recommended to be the most effective therapies for the first-line treatment of uncomplicated falciparum malaria. "
01/01/2011 - "Artemisinin-combination therapy is a highly effective treatment for uncomplicated falciparum malaria but parasite recrudescence has been commonly reported following artemisinin (ART) monotherapy. "
09/01/2010 - "Artemisinin-based combination therapies (ACTs) are highly effective for the treatment of Plasmodium falciparum malaria, yet their sustained efficacy is threatened by the potential spread of parasite resistance. "
01/01/2006 - "Artemisinin-containing therapies are highly effective against Plasmodium falciparum malaria. "
12/01/2002 - "Artemisinin-derivative combination therapies (ACT) are highly efficacious against multidrug-resistant Plasmodium falciparum malaria. "

08/14/2009 - "In combination with other drugs (artemisinin combination therapy), these compounds are the first-line treatment recommended by the World Health Organization for Plasmodium falciparum infections. "
01/01/2009 - "This is because the various forms of ACT are more effective against infections with artemisinin-sensitive parasites, leaving the more resistant infections as an increasing proportion of the dwindling parasite population. "
08/01/1997 - "Pure artemisinin thus appears to be effective against at least two coccidia species when used as a feed additive, and its activity may depend, in part, on the length of time it is administered before a challenge infection."
12/15/2015 - "Four experiments were conceived in order to test the efficacy of artemisinin, a sesquiterpene lactone derived from Artemisia annua, in single experimental infection of broiler chickens with Eimeria acervulina(1×10(5) oocysts), Eimeria maxima (5×10(4) oocysts) or Eimeria tenella (1×10(4) oocysts), and mixed infection with all 3 species (3.2×10(4)Eimeria spp. oocysts). "
01/01/2014 - "Retracted: A Study on Course of Infection and Haematological Changes in falciparum-Infected in Comparison with Artemisinin(s)-Treated Mice."

10/20/2015 - "The isoxazolidine-containing spirobicyclic artemalogue 11b turns out to be the most potent with low micromolar IC50 values against all three tumor cells, which were at least 4- to 14-fold more potent than the parent artemisinin. "
02/01/2013 - "However, simple artemisinin analogs are less potent than traditional cancer chemotherapeutic agents and have short plasma half-lives, and would require high dosage and frequent administration to be effective for cancer treatment. "
10/01/2014 - "A combination therapy with artemisinin can be more effective against cancer cells than monotherapy with that. "
06/01/2014 - "Recent population studies suggest that the use of artemisinin is associated with reduced incidence and improved prognosis of certain cancers. "
02/01/2014 - "Recent population studies suggest that the use of artemisinin is associated with reduced incidence and improved prognosis of certain cancers. "

05/01/2014 - "Artemisinin (ARMN) is a potent antimalarial drug, which is effective against multidrug resistant strains of Plasmodium falciparum and produces rapid recovery even in patients with cerebral malaria. "
04/01/2011 - "Artemisinin has rather low toxicity; it is effective against drug-resistant Plasmodium species and against cerebral malaria. "
06/01/1982 - "Clinical studies on treatment of cerebral malaria with qinghaosu and its derivatives."
10/08/2015 - "Artemisinin-NO-donor hybrid compounds show promise as potential new drugs for treating cerebral malaria. "
01/01/2015 - "The mortality rate in Human Cerebral Malaria (HCM) is unacceptably high (15-20%), despite the availability of artemisinin-based therapy. "