(2-cyano-3-(methylamino)phenyl)oxoacetic acid

orally active antiallergy agent; RN given is for Na salt

Also Known As:

(2-cyano-3-(methylamino)phenyl)oxoacetate; (2-cyano-3-(methylamino)phenyl)oxoacetic acid sodium salt; Wy 41,195; Wy 41195; Wy-41,195; Wy-41195; acetic acid, ((2-cyano-3-(methylamino)phenyl)amino)oxo-, monosodium salt

Networked: 3 relevant articles (1 outcomes, 0 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Related Diseases

1.	Asthma (Bronchial Asthma) 01/01/1982 - "Activity in these animal systems indicates that Wy-41,195 may hold promise in the treatment of bronchial asthma and other allergic diseases in man."
2.	Hypersensitivity (Allergy) 01/01/1984 - "Furthermore, Wy-41,195 was ineffective against methacholine hypersensitivity when administered orally for 4 days. " 01/01/1984 - "Both Wy-41,195 and disodium cromoglycate, two antiallergic drugs, inhibited the hypersensitivity to methacholine when administered just prior to methacholine challenge. "
3.	Anaphylaxis (Anaphylactic Shock) 01/01/1985 - "Wy-41,195 demonstrated significant inhibitory effects (54-60%) when administered topically at 0.25-2% concentrations in a rat passive eyelid anaphylaxis assay. " 01/01/1985 - "The topical effects of Wy-41,195 [2-cyano-3-(methylamino)phenylamino] oxoacetic acid, sodium salt and disodium cromoglycate in the rat passive eyelid anaphylaxis."

Related Drugs and Biologics

1.	Cromolyn Sodium (Cromoglicic Acid)
2.	Anti-Allergic Agents (Antiallergic Agents)
3.	Methacholine Chloride (Methacholine)
4.	Sodium
5.	Salts
6.	Acids