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diclofensine

RN given refers to parent cpd(+-)-isomer; structure given in first source

Also Known As:

Ro 8-4650; diclofensine hydrochloride

Networked: 6 relevant articles (0 outcomes, 1 trials/studies)

Bio-Agent Context: Research Results

Heterocyclic Compounds: 198
- Fused-Ring Heterocyclic Compounds
  - 2-Ring Heterocyclic Compounds
    - Isoquinolines: 34
      - diclofensine: 6

Related Diseases

1.	Depressive Disorder (Melancholia) 11/01/1982 - "The objective of this double-blind trial was to assess the effect of diclofensine on geriatric patients with depressive syndromes in comparison to placebo. " 11/01/1982 - "[Clinical double blind comparison of diclofensine and placebo in geriatric patients with depressive syndromes]."
2.	Parkinson Disease (Parkinson's Disease) 07/01/1978 - "Dopaminergic agonist Ro 8-4650 in Parkinson's disease. " 07/01/1978 - "Dopaminergic agonist Ro 8-4650 in Parkinson's disease. "
3.	Dizziness (Lightheadedness) 01/01/1985 - "The most frequently reported side effects in the diclofensine-treated patients were dry mouth, insomnia, dizziness, and agitation. " 03/01/1984 - "One patient (diclofensine group) reported a transient slight somnolence, the other (placebo group) reported episodes of transient dizziness. "
4.	Sleep Initiation and Maintenance Disorders (Insomnia) 01/01/1985 - "The most frequently reported side effects in the diclofensine-treated patients were dry mouth, insomnia, dizziness, and agitation. "
5.	Hemolysis 08/01/1991 - "In an attempt to determine the antigenic combining sites of drug-dependent antibodies in patients with drug-related immune haemolysis, we have assessed the reactivity of 35 nomifensine-induced antibodies against human red blood cells (RBC) in the presence of 11 closely related compounds: nomifensine, its three main metabolites including their methoxylated analogues and diclofensine with its three main metabolites. "

Related Drugs and Biologics

1.	Dopamine Agonists (Dopamine Agonist)
2.	Nomifensine (Nomifensin)
3.	Antibodies