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ribose 1-phosphate
RN given refers to (D)-isomer
Also Known As:
alpha-D-ribofuranose 1-phosphate; ribose 1-phosphate, (alpha-D)-isomer; ribose 1-phosphate, (beta-D)-isomer
Networked:
5
relevant articles (
1
outcomes,
0
trials/studies)
Relationship Network
Bio-Agent Context: Research Results
Carbohydrates: 22023
Sugar Phosphates: 20
Pentosephosphates
Ribosemonophosphates
ribose 1-phosphate: 5
Related Diseases
1.
Neoplasms (Cancer)
02/01/1977 - "
Determination of ribose 1-phosphate in ascites tumor cells.
"
12/14/1977 - "
Ribose 1-phosphate concentrations have been measured in tumor cells incubated with purine and pyrimidine nucleosides and with glucose.
"
04/01/1983 - "
Both ribose 1-phosphate and deoxyribose 1-phosphate, which were effective in increasing the formation of antineoplastic fluoronucleotides and fluoro-RNA from 5-fluorouracil (5-FU) in the intact cells of Ehrlich mouse ascites tumor, potentiated the antitumor effect of 5-FU.
"
12/14/1977 - "
Although uridine was cleaved at approximately the same rate as inosine, as judged by lactate accumulation, concentrations of ribose 1-phosphate that accumulated were only approximately 0.06 mumol/ml. Ribose 1-phosphate accumulation in tumor cells incubated with inosine was dependent on the phosphate concentration of the medium up to at least 25 mM. Ribose 1-phosphate formed from inosine was readily converted both to phosphoribosyl pyrophosphate and to lactate.
"
08/01/1977 - "
The effects of orthophosphate concentration on the accumulation of lactate and of phosphoribosyl pyrophosphate and on concentrations of ribose 1-phosphate and ribose 5-phosphate in tumor cells incubated with glucose were also determined.
"
2.
Ascites
02/01/1977 - "
Determination of ribose 1-phosphate in ascites tumor cells.
"
04/01/1983 - "
Both ribose 1-phosphate and deoxyribose 1-phosphate, which were effective in increasing the formation of antineoplastic fluoronucleotides and fluoro-RNA from 5-fluorouracil (5-FU) in the intact cells of Ehrlich mouse ascites tumor, potentiated the antitumor effect of 5-FU.
"
3.
Ehrlich Tumor Carcinoma
12/14/1977 - "
Ribose 1-phosphate metabolism in Ehrlich ascites tumor cells in vitro.
"
11/01/1982 - "
We studied the uptake of radioactive 5-fluorouracil (FUra) by the intact cells of Ehrlich ascites tumor in the presence of various coreactants with FUra such as uridine (Urd), deoxyuridine (dUrd), ribose 1-phosphate (Rib1P), and deoxyribose 1-phosphate (dRib1P).
"
Related Drugs and Biologics
1.
Fluorouracil (Carac)
2.
Deoxyribose
3.
RNA (Ribonucleic Acid)
4.
Antineoplastic Agents (Antineoplastics)
5.
Lactic Acid (Lactate)
6.
Uridine
7.
Phosphoribosyl Pyrophosphate
8.
Phosphates (Orthophosphate)
9.
Glucose (Dextrose)
10.
Pyrimidine Nucleosides