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glycolic acid (glycolate)

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RN given refers to parent cpd

Also Known As:

glycolate; hydroxyacetic acid; glycolic acid, 1-(14)C-labeled; glycolic acid, 2-(14)C-labeled; glycolic acid, calcium salt; glycolic acid, monoammonium salt; glycolic acid, monolithium salt; glycolic acid, monopotassium salt; glycolic acid, monosodium salt; glycolic acid, potassium salt

Networked: 312 relevant articles (43 outcomes, 56 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 58
- Carboxylic Acids: 83
  - Hydroxy Acids: 24
    - Glycolates
      - glycolic acid: 312

Experts

1.	Sarkar, Rashmi: 4 articles (01/2009 - 09/2002)
2.	Wang, Yan: 3 articles (11/2014 - 09/2009)
3.	McMartin, Kenneth E: 3 articles (05/2014 - 03/2005)
4.	Matsunaka, Hiroshi: 3 articles (03/2014 - 10/2010)
5.	Funasaka, Yoko: 3 articles (10/2010 - 01/2003)
6.	Guevara, Ian L: 3 articles (03/2010 - 12/2002)
7.	Pandya, Amit G: 3 articles (03/2010 - 12/2002)
8.	Huang, Leaf: 2 articles (11/2015 - 06/2007)
9.	Zilberman, Meital: 2 articles (08/2015 - 05/2010)
10.	Wang, Dong: 2 articles (12/2014 - 03/2013)

Related Diseases

1.	Melanosis (Freckles) 06/01/2013 - "Previous studies have shown that use of a brightening system comprised of 0.01% decapeptide-12 cream, an antioxidant cleanser, a 20% buffered glycolic acid lotion, and a broad spectrum SPF 30 sunscreen yields good clearance of mild-to-moderate melasma in Caucasian and Asian volunteers. " 03/01/2012 - "To compare the therapeutic efficacy of low fluence QSNYL, high fluence QSNYL, and glycolic acid peel in melasma in three study groups of 25 patients each. " 01/01/2015 - "Both TCA and glycolic acid peels were effective in frictional melanosis. " 03/01/1997 - "This study was undertaken to see if glycolic acid peels are effective and safe in the treatment of melasma and fine facial wrinkling. " 01/01/2015 - "Chemical peeling with both tricholoroacetic acid (15%) and glycolic acid (50%) is safe and effective for the treatment of frictional dermal melanosis. "
2.	Acne Vulgaris 09/01/2011 - "The 10% glycolic acid containing oil-in-water emulsion improved mild acne applied as monotherapy in this study significantly, already after 45 days of treatment. " 06/01/2014 - "In this clinical trial, a topical cleansing product containing glycolic acid with pH 4 improved mild acne significantly following twice-daily application for 6 weeks as monotherapy." 03/01/1999 - "Glycolic acid chemical peels are an effective treatment for all types of acne, inducing rapid improvement and restoration to normal looking skin." 08/01/2014 - "Our study is aimed to evaluate the efficacy and tolerability of a combination therapy with Retinaldheyde (0.1%), Glycolic acid (6%) and Efectiose (0.1%) (RGE) cream in patients affected by acne vulgaris, during the lasting period of sun exposure. " 06/01/2014 - "The aim of the study was to investigate a topical cleansing product containing glycolic acid with pH 4 in mild acne vulgaris. "
3.	Hyperpigmentation 04/01/2012 - "This prospective study evaluated the safety and efficacy of decapeptide-12 in conjunction with an antioxidant cleanser, glycolic-acid containing facial moisturizer and broad-spectrum sunscreen in the treatment of facial hyperpigmentation associated with chronic photodamage. " 01/01/2007 - "Three patients in the glycolic acid peel group developed a mild-degree postinflammatory hyperpigmentation with total clearance at the end of the treatment period. " 03/01/1997 - "This pilot study demonstrates that serial glycolic acid peels provide an additional benefit, with minimal adverse effects, for the treatment of postinflammatory hyperpigmentation in dark-complexioned individuals." 03/01/1997 - "Glycolic acid peels for postinflammatory hyperpigmentation in black patients. " 12/01/2003 - "Glycolic acid has been added to hydroquinone formulations in the past to enhance their depigmentation effects, but may cause irritation, leading to postinflammatory hyperpigmentation. "
4.	Cicatrix (Scar) 12/01/2011 - "A combination of microneedling and glycolic acid (GA) peels was found to give excellent results in the treatment of such scars. " 10/01/2000 - "Although many clinical studies have been performed to investigate the efficacy of glycolic acid in the treatment of acne vulgaris, to the best of our knowledge no placebo-controlled study has been carried out to ascertain the effect of glycolic acid on atrophic postacne scars. " 12/01/2011 - "Combination of microneedling and glycolic acid peels for the treatment of acne scars in dark skin." 10/01/2000 - "Glycolic acid peeling is an effective modality for the treatment of atrophic acne scars, but repetitive peels (at least six times) with 70% concentration are necessary to obtain evident improvement. " 10/01/2000 - "Biweekly serial glycolic acid peels vs. long-term daily use of topical low-strength glycolic acid in the treatment of atrophic acne scars."
5.	Neoplasms (Cancer) 10/01/2006 - "In this review, a set of guidelines for chemical peeling is introduced, and we will discuss several clinical and histological studies including the effects of glycolic acid, and the application of deer peeling to skin tumors in our department." 11/01/2004 - "Future studies focusing on cell signaling and biological significance of glycolic acid-induced apoptosis would lead to exploring the mechanisms of chemotherapeutic potency of glycolic acid in human cancers." 12/05/2002 - "In this study we investigated anti-tumor promoting mechanism of glycolic acid on the UV-induced skin tumor development. " 09/01/2007 - "The addition of glycolic acid (4% or 10%) did not affect the time to tumor in male or female mice at either SSL dose when compared to mice receiving the control cream. " 12/05/2002 - "We previously found that glycolic acid inhibited UV-induced skin tumor development in hairless mouse. "

Related Drugs and Biologics

1.	hydroquinone (Black and White)
2.	polylactic acid-polyglycolic acid copolymer (PLGA)
3.	Carbon Monoxide
4.	Tretinoin (Retinoic Acid)
5.	azelaic acid (Azelex)
6.	Salicylic Acid (2 Hydroxybenzoic Acid)
7.	Lactic Acid
8.	Retinaldehyde (Retinal)
9.	kojic acid
10.	Hyaluronic Acid (Hyaluronan)

Related Therapies and Procedures

1.	Microspheres (Microsphere)
2.	Skin Care
3.	Solid-State Lasers
4.	Lasers (Laser)
5.	Transplants (Transplant)