glycolic acid (glycolate)

RN given refers to parent cpd

Also Known As:

glycolate; hydroxyacetic acid; glycolic acid, 1-(14)C-labeled; glycolic acid, 2-(14)C-labeled; glycolic acid, calcium salt; glycolic acid, monoammonium salt; glycolic acid, monolithium salt; glycolic acid, monopotassium salt; glycolic acid, monosodium salt; glycolic acid, potassium salt; potassium glycolate

Networked: 569 relevant articles (80 outcomes, 113 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Organic Chemicals: 133
- Carboxylic Acids: 973
  - Hydroxy Acids: 94
    - Glycolates
      - glycolic acid: 569
  - Acyclic Acids
    - Acetates: 4994
      - Glycolates
        glycolic acid: 569

Experts

1.	Sarkar, Rashmi: 7 articles (07/2019 - 09/2002)
2.	Dayal, Surabhi: 5 articles (11/2021 - 10/2013)
3.	McMartin, Kenneth E: 4 articles (01/2022 - 03/2005)
4.	Sahu, Priyadarshini: 4 articles (11/2021 - 03/2017)
5.	Wang, Yan: 4 articles (05/2018 - 09/2009)
6.	Funasaka, Yoko: 4 articles (10/2017 - 01/2003)
7.	Hoffman, Robert S: 3 articles (01/2022 - 04/2009)
8.	Tian, Yan: 3 articles (06/2021 - 11/2016)
9.	Wang, Zhigang: 3 articles (08/2020 - 01/2017)
10.	Garg, Vijay Kumar: 3 articles (07/2019 - 08/2008)

Related Diseases

1.	Melanosis (Freckles) 03/01/2012 - "To compare the therapeutic efficacy of low fluence QSNYL, high fluence QSNYL, and glycolic acid peel in melasma in three study groups of 25 patients each. " 01/01/2017 - "Results showed that triple-combination was found to be an effective and safe peeling agent in the treatment of melasma and it was as effective as 50% glycolic acid peel." 01/01/2015 - "Both TCA and glycolic acid peels were effective in frictional melanosis. " 03/01/1997 - "This study was undertaken to see if glycolic acid peels are effective and safe in the treatment of melasma and fine facial wrinkling. " 03/01/2012 - "This study shows the efficacy of low-fluence QSNYL and glycolic acid peel in melasma. "
2.	Acne Vulgaris 06/01/2014 - "In this clinical trial, a topical cleansing product containing glycolic acid with pH 4 improved mild acne significantly following twice-daily application for 6 weeks as monotherapy." 03/01/1999 - "Glycolic acid chemical peels are an effective treatment for all types of acne, inducing rapid improvement and restoration to normal looking skin." 10/01/2017 - "The aim of this study was to investigate the efficacy of 50% glycolic acid peeling performed at different phases of menstruation on acne. " 06/01/2014 - "The aim of the study was to investigate a topical cleansing product containing glycolic acid with pH 4 in mild acne vulgaris. " 04/01/2012 - "The purpose of this study was to identify the mechanism of glycolic acid chemical peeling to improve inflammatory acne. "
3.	Hyperpigmentation 04/01/2017 - "Treatment of Postinflammatory Hyperpigmentation With a Combination of Glycolic Acid Peels and a Topical Regimen in Dark-Skinned Patients: A Comparative Study." 01/01/2007 - "Three patients in the glycolic acid peel group developed a mild-degree postinflammatory hyperpigmentation with total clearance at the end of the treatment period. " 03/01/1997 - "This pilot study demonstrates that serial glycolic acid peels provide an additional benefit, with minimal adverse effects, for the treatment of postinflammatory hyperpigmentation in dark-complexioned individuals." 03/01/1997 - "Glycolic acid peels for postinflammatory hyperpigmentation in black patients. " 06/26/2021 - "A high concentration of glycolic acid significantly improved skin roughness as well as follicular hyperpigmentation of patients with keratosis pilaris. "
4.	Cicatrix (Scar) 12/01/2017 - "Addition of sequential 70% glycolic acid peel to microneedling gives better scar improvement as compared to microneedling alone. " 12/01/2011 - "A combination of microneedling and glycolic acid (GA) peels was found to give excellent results in the treatment of such scars. " 10/01/2000 - "Although many clinical studies have been performed to investigate the efficacy of glycolic acid in the treatment of acne vulgaris, to the best of our knowledge no placebo-controlled study has been carried out to ascertain the effect of glycolic acid on atrophic postacne scars. " 10/01/2000 - "Glycolic acid peeling is an effective modality for the treatment of atrophic acne scars, but repetitive peels (at least six times) with 70% concentration are necessary to obtain evident improvement. " 10/01/2000 - "Biweekly serial glycolic acid peels vs. long-term daily use of topical low-strength glycolic acid in the treatment of atrophic acne scars."
5.	Infections 04/15/2010 - "A combined chemical-biological treatment, applied at laboratory scale by use of glycolic acid (2%) and isolated bacteriophages against Sphaerotilus natans (SN1 and ER1-a newly isolated phage) at low multiplicity of infection (MOI), showed inhibition of biofilm formation and inactivation of the contaminant bacteria. " 01/13/2021 - "Metabolite profiling of phloem sap-enriched exudates revealed that glycolate and aspartate levels were affected by the infection. " 10/01/2014 - "After examination and ruling out any infection, petroleum jelly was applied on the cuticle margins of the nails for protection and 70% glycolic acid was applied over the nail plate for 45 minutes. " 06/01/1998 - "Encapsulation of recombinant adenovirus vectors in poly(lactic/glycolic acid) (PLGA) copolymer enables infection in vitro, in the presence of neutralizing antibodies and results in the release of viable virus for over 100 h. " 09/01/2016 - "Short communication: Efficacy of glycolic acid-based and iodine-based postmilking barrier teat disinfectants for prevention of new intramammary infections in dairy cattle."

Related Drugs and Biologics

1.	hydroquinone (Esoterica)
2.	poly(lactide) (polylactic acid)
3.	Salicylic Acid (2 Hydroxybenzoic Acid)
4.	Tretinoin (Retinoic Acid)
5.	Trichloroacetic Acid
6.	Sunscreening Agents (Sunscreens)
7.	azelaic acid (Azelex)
8.	Lactic Acid (Lactate)
9.	Acids
10.	Antioxidants

Related Therapies and Procedures

1.	Microspheres (Microsphere)
2.	Therapeutics
3.	Skin Care
4.	Percutaneous Collagen Induction
5.	Lasers (Laser)