11- deoxy- 11alpha- (2- hydroxyethylthio)- prostaglandin E2 methyl ester

Also Known As:

11-deoxy-11alpha-(2-hydroxyethylthio)-PGE2 methyl ester; DHET-PGE2; Prosta-5,13-dien-1-oic acid, 15-hydroxy-11-((2-hydroxyethyl)thio)-9-oxo-, methyl ester, (5Z,11alpha,13E,15S)-

Networked: 1 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Lipids: 114793
- Fatty Acids: 27405
  - Unsaturated Fatty Acids: 8236
    - Eicosanoids: 3262
      - Prostaglandins: 17100
        Prostaglandins E: 2673
        Dinoprostone: 10047
        11-deoxy-11alpha-(2-hydroxyethylthio)-prostaglandin E2 methyl ester: 1
Biological Factors: 2472
- Inflammation Mediators: 1113
  - Autacoids: 276
    - Eicosanoids: 3262
      - Prostaglandins: 17100
        Prostaglandins E: 2673
        Dinoprostone: 10047
        11-deoxy-11alpha-(2-hydroxyethylthio)-prostaglandin E2 methyl ester: 1

Related Diseases

Bronchial Spasm

03/01/1981 - "A C-11 substituted PGE2 analog, DHET-PGE2 [alpha-11-deoxy-11 alpha-(2-hydroxyethylthio)-PGE2 methyl ester], was demonstrated to exert potent bronchodilator activity in three in vivo models of augmented airway resistance: (1) acute bronchospasms, induced by 5-hydroxytryptamine, histamine and acetylcholine in the anesthetized guinea pig, (2) acute bronchospasm, induced by pilocarpine, in the anesthetized dog, and (3) chronic bronchospasm, induced by SO2 exposure, in the unanesthetized dog. "

Related Drugs and Biologics

1.	Dinoprostone (PGE2)
2.	Serotonin (5 Hydroxytryptamine)
3.	Pilocarpine (Ocusert)
4.	Histamine (Histamine Dihydrochloride)
5.	Esters
6.	Bronchodilator Agents (Bronchodilators)
7.	Acetylcholine (Acetylcholine Chloride)