Bacillus Thuringiensis insecticidal crystal protein

insecticidal crystal proteins are a group of bacterial endotoxins encoded by strains of B. thuringiensis during sporulation and deposited in the cytoplasm as inclusions; control agricultural pests; has been partially sequenced

Also Known As:

insecticidal crystal protein, Bacillus Thuringiensis; B.T.K. insect control protein, Bacillus thuringiensis; BT crystal protein, Bacillus thuringiensis; BT glycoprotein toxin, Bacillus thuringiensis; Bacillus thuringiensis cry proteins; Bacillus thuringiensis crystal proteins; Bacillus thuringiensis crystal toxins; Cry10Aa protein, Bacillus thuringiensis; Cry11Aa protein, Bacillus thuringiensis; Cry19B protein, Bacillus thuringiensis; Cry1Aa delta-endotoxin, Bacillus thuringiensis; Cry1Aa toxin protein, Bacillus thuringiensis; Cry1Ab protein, Bacillus thuringiensis; Cry27A protein, Bacillus thuringiensis; Cry2A protein, Bacillus thuringiensis; Cry3A endotoxin, Bacillus Thuringiensis; Cry3Aa11 protein, Bacillus thuringiensis; Cry3Ba protein, Bacillus thuringiensis; Cry45Aa protein, Bacillus thuringiensis; Cry5B toxin, Bacillus thuringiensis; Cry6A toxin, Bacillus thuringiensis; Cry9A endotoxin, Bacillus Thuringiensis; Cry9c protein, Bacillus thuringiensis; CryIA(a) protein, Bacillus thuringiensis; CryIA(c) protein, Bacillus thuringiensis; CryIB protein, Bacillus thuringiensis; CryIG delta-endotoxin protein, Bacillus thuringiensis; CryIIA protein, Bacillus thuringiensis; CryIIB protein, Bacillus thuringiensis; CryIVA protein, Bacillus thuringiensis; CryIVB delta-endotoxin protein, Bacillus thuringiensis; CryIVD protein, Bacillus thuringiensis; CryIc protein, Bacillus thuringiensis; Cyt1Aa protein, Bacillus thuringiensis; Cyt1Ab1 protein, Bacillus thuringiensis; Cyt1Ca protein, Bacillus thuringiensis; cry toxins; cry1Ac protein, Bacillus thuringiensis; cry3Aa protein, Bacillus thuringiensis; cry4Aa protein, Bacillus thuringiensis; cry4Ba protein, Bacillus thuringiensis; cry7 protein, Bacillus thuringiensis; cry9Da protein, Bacillus thuringiensis; cryIA(b) protein, Bacillus thuringiensis; cryII protein, Bacillus thuringiensis; cryIIIA protein, Bacillus thuringiensis; crystal protein, Bacillus Thuringiensis; crystal toxins; cyt2Aa1 protein, Bacillus thuringiensis; cyt2Ba1 protein, Bacillus thuringiensis; cytB protein, Bacillus thuringiensis; delta Endotoxins; delta endotoxin protein, Bacillus thuringiensis; delta-endotoxin protein, Bacillus thuringiensis

Networked: 17 relevant articles (0 outcomes, 0 trials/studies)

Bio-Agent Context: Research Results

Experts

1.	Bravo, Alejandra: 3 articles (01/2019 - 03/2010)
2.	Mendoza-Almanza, Gretel: 2 articles (01/2020 - 01/2019)
3.	Soberón, Mario: 2 articles (01/2019 - 01/2018)
4.	Ammons, David R: 2 articles (02/2016 - 05/2011)
5.	Short, John D: 2 articles (02/2016 - 05/2011)
6.	Chen, Haibo: 1 article (01/2022)
7.	Lereclus, Didier: 1 article (01/2022)
8.	Slamti, Leyla: 1 article (01/2022)
9.	Verplaetse, Emilie: 1 article (01/2022)
10.	Lemeshko, Victor V: 1 article (01/2021)

Related Diseases

1.	Neoplasms (Cancer) 09/01/2019 - "A novel group of Cry toxins called parasporins possess a strong cytocidal activity against some human cancer cells. " 01/01/2019 - "The capacity of Cry toxins to eliminate tumors in xenograft mouse models was also analyzed. " 01/01/2018 - "Parasporins are Cry toxins that are toxic to cancer cell lines that have structural similarities with the insecticidal Cry toxins. " 02/01/2016 - "However, some Cry toxins, called parasporins (PSs), are non-insecticidal and have been shown to differentially kill human cancer cells. " 05/01/2011 - "Unlike Cry toxins that demonstrate activity mainly against some insect cells, parasporins are characterized as being non-hemolytic, yet capable of preferentially killing some human cancer cells. "
2.	Infections 01/01/2016 - "These results implicate BTI_23p as a plasmid that is required for successful infection, yet unstable when present at high frequency in the population, consistent with the role of Cry toxins as public goods. " 01/01/2016 - "Bacillus thuringiensis is an invertebrate pathogen that uses plasmid-encoded crystal (Cry) toxins to establish infections inside the host. " 01/01/2019 - "We further confirmed that the vegetative Bt cells trigger a quorum sensing response that is activated by PlcR regulator, resulting in production of different virulence factors, such as the metalloproteinases ColB and Bmp1, that besides Cry toxins are necessary to disrupt the nematode epithelial junctions causing efficient bacterial host infection and death of the nematode. "
3.	Weight Gain 10/20/1995 - "The order of toxicity of the delta-endotoxins, as measured by the dose required for a 50% inhibition of weight gain (ID50), was CryIAa (77.3 ng) > CryIAb (157 ng) > CryIAc (187 ng). "
4.	Yellow Fever 01/28/2014 - "Bacillus thuringiensis (Bt) Cry toxins are used to control Aedes aegypti, an important vector of dengue fever and yellow fever. "
5.	Toxemia 01/01/2022 - "thuringiensis infectious cycle in insects, in addition to the primary role of the Cry toxins in the toxemia caused by ingestion of crystals."

Related Drugs and Biologics

1.	Proteins (Proteins, Gene)
2.	Metalloproteases (Metalloproteinases)
3.	Virulence Factors (Pathogenicity Factors)
4.	Trypsin
5.	Peptide Hydrolases (Proteases)