pendimethalin (Prowl)

05/01/2006 - "There was some evidence for an elevated risk for lung cancer, but the excess occurred only in the highest exposure category for lifetime pendimethalin exposure. "
12/01/2018 - "In this study, we examined the apoptotic and anti-apoptotic potentials of pendimethalin and trifluralin on A549 human non-small lung cancer cells with several concentrations in vitro. "
01/01/2017 - "These analyses provide additional evidence for an association between pendimethalin, dieldrin, and parathion use and lung cancer risk. "
01/01/2016 - "Some evidence of exposure-response of metolachlor and pendimethalin for lung cancer and an association of metribuzin with risk of glioma have been reported. "
11/01/2004 - "Two widely used herbicides, metolachlor and pendimethalin (for low-exposed groups to four higher exposure categories: odds ratio (OR) = 1.0, 1.6, 1.2, 5.0; p(trend) = 0.0002; and OR = 1.0, 1.6, 2.1, 4.4; p(trend) = 0.003, respectively), and two widely used insecticides, chlorpyrifos and diazinon (OR = 1.0, 1.1, 1.7, 1.9; p(trend) = 0.03; and OR = 1.0, 1.6, 2.7, 3.7; p(trend) = 0.04, respectively), showed some evidence of exposure response for lung cancer. "

10/01/2022 - "This study provides previously unrecognized adverse effects of pendimethalin in vascular endothelial cells, mediated by ER stress-induced mitochondrial dysfunction."
10/01/2022 - "Pendimethalin induces apoptotic cell death through activating ER stress-mediated mitochondrial dysfunction in human umbilical vein endothelial cells."
02/01/2018 - "Pendimethalin induces oxidative stress, DNA damage, and mitochondrial dysfunction to trigger apoptosis in human lymphocytes and rat bone-marrow cells."
09/01/2023 - "The structurally homologous substances ethalfluralin and pendimethalin, which belong to the dinitroaniline family, were found to be genotoxic and to exert developmental toxicity via mitochondrial dysfunction in a zebrafish model. "
04/01/2021 - "The mitochondrial defects were evaluated after administering tilapia fish, Oreochromis niloticus to sublethal doses (1.02 and 5.10 mg kg-1) of the herbicide pendimethalin (PD). "

03/01/2009 - "There have been some reported acute pendimethalin poisoning cases in humans and most of them intentionally ingested the concentrated formulation. "
06/01/1998 - "Clinical experience with pendimethalin (STOMP) poisoning in Taiwan."
08/01/2015 - "Therefore, this study investigated the clinical characteristics of acute intentional pendimethalin herbicide poisoning. "
06/01/2013 - "Emergence of new poisons: a case of pendimethalin poisoning from rural India."

05/01/2006 - "We did not find a clear association of lifetime pendimethalin exposure either with overall cancer incidence or with specific cancer sites."
05/01/2006 - "Overall cancer incidence did not increase with increasing lifetime pendimethalin use, and there was no clear evidence of an association between pendimethalin use and risks for specific cancers. "
05/01/2006 - "We conducted Poisson regression analyses to evaluate the association of pendimethalin exposure with cancer incidence (mean follow-up = 7.5 years) using two exposure metrics: tertiles of lifetime days of exposure and tertiles of intensity-weighted lifetime days of exposure. "
08/01/2020 - "The obtained results may draw attention to the usage and possible toxic effect of pendimethalin due to oxidative damage induction; however, detailed inflammation mechanisms and other cancer pathways should be investigated."
12/01/2018 - "Twenty-four hours' exposure with 100 μM pendimethalin and trifluralin altered the gene expressions, suppressing apoptosis and allowing cancer cells to grow and proliferate. "

08/08/2013 - "The prevention and reduction of weight loss in an acute tertiary care setting: protocol for a pragmatic stepped wedge randomised cluster trial (the PRoWL project)."
06/19/2020 - "The degradation process of the obtained polymeric microspheres was evaluated based on (1) their weight loss and surface erosion and (2) the release rate of loaded metazachlor and pendimethalin. "