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gluconic acid (gluconate)

Subscribe to New Research on gluconic acid

RN given refers to (D)-isomer; all RRs refers to (D)-isomer unless otherwise noted

Also Known As:

gluconate; zinc gluconate; sodium gluconate; magnesium gluconate; D-gluconate; D-gluconic acid; Wörwag brand of magnesium gluconate; boron gluconate; gluconic acid, (113)indium-labeled; gluconic acid, (14)C-labeled; gluconic acid, (159)dysprosium-labeled salt; gluconic acid, (99)technecium (5+) salt; gluconic acid, 1-(14)C-labeled; gluconic acid, 6-(14)C-labeled; gluconic acid, Fe(+2) salt, dihydrate; gluconic acid, aluminum (3:1) salt; gluconic acid, ammonium salt; gluconic acid, calcium salt; gluconic acid, cesium(+3) salt; gluconic acid, cobalt (2:1) salt; gluconic acid, copper salt; gluconic acid, lanthanum(+3) salt; gluconic acid, magnesium (2:1) salt; gluconic acid, manganese (2:1) salt; gluconic acid, monolithium salt; gluconic acid, monopotassium salt; gluconic acid, monosodium salt; gluconic acid, potassium salt; gluconic acid, sodium salt; gluconic acid, strontium (2:1) salt; gluconic acid, tin(+2) salt; gluconic acid, zinc salt; lithium gluconate; magnerot; manganese gluconate

Networked: 338 relevant articles (37 outcomes, 50 trials/studies)

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Drug Context: Research Results

Experts

1.	Thakur, C P: 7 articles (07/2008 - 01/2001)
2.	Dreno, Brigitte: 5 articles (09/2012 - 11/2002)
3.	Sundar, Shyam: 4 articles (08/2015 - 08/2003)
4.	Roy, Syamal: 4 articles (03/2015 - 05/2006)
5.	Narayan, S: 4 articles (06/2008 - 07/2003)
6.	Singh, Neeloo: 3 articles (01/2014 - 08/2003)
7.	Chatterjee, Mitali: 3 articles (01/2014 - 02/2007)
8.	Eby, George A: 3 articles (03/2010 - 02/2004)
9.	Moyse, Dominique: 3 articles (03/2010 - 11/2002)
10.	Moyse, D: 3 articles (04/2007 - 01/2001)

Related Diseases

1.	Common Cold 03/01/1997 - "A randomized, double-blind, placebo-controlled clinical trial has shown that treatment of the common cold with zinc gluconate lozenges resulted in a significant reduction in duration of symptoms of the cold. " 02/01/2006 - "Commercial preparations of intranasal zinc gluconate gel are marketed as a remedy for the common cold. " 07/15/1996 - "To test the efficacy of zinc gluconate lozenges in reducing the duration of symptoms caused by the common cold. " 01/01/1987 - "A recently published randomized, controlled, double-blind, study has reported efficacy of zinc gluconate lozenge treatment of the common cold. " 01/01/1999 - "Some studies support the use of zinc gluconate lozenges to treat the common cold, but there are insufficient data at this time to recommend the routine use of these lozenges. "
2.	Visceral Leishmaniasis (Kala Azar) 06/01/1985 - "Sodium stibo-gluconate failed in one of three kala-azar patients and in one of two patients with cutaneous leishmaniasis. " 02/01/2007 - "The resistance of clinical isolates of Leishmania donovani to sodium antimony gluconate (SAG), the mainstay of treatment in Indian visceral leishmaniasis, has become a critical issue in India. " 12/01/1998 - "Sodium antimony gluconate (SAG) is the mainstay of treatment for visceral leishmaniasis (VL) or kala-azar. " 08/01/2015 - "Resistance emergence against antileishmanial drugs, particularly Sodium Antimony Gluconate (SAG) has severely hampered the therapeutic strategy against visceral leishmaniasis, the mechanism of resistance being indistinguishable. " 11/01/2013 - "Resistance to sodium antimony gluconate (SAG) is a major cause of therapeutic failure in a large proportion of visceral leishmaniasis (VL) cases. "
3.	Infection 12/01/2010 - "Daily chlorohexidine gluconate bathing with impregnated cloths results in statistically significant reduction in central line-associated bloodstream infections." 08/01/1987 - "The therapeutic efficacy of zinc gluconate lozenge therapy in experimentally induced rhinovirus infection was assessed in two randomized controlled trials in susceptible adult volunteers. " 12/01/2001 - "The purpose of these studies was to evaluate the effectiveness of intranasal zinc gluconate for prevention of experimental rhinovirus infection and illness. " 01/01/2014 - "The results have been compared with those obtained on the same samples with a commercial kit based on a spectrophotometric enzyme assay and were in good agreement, showing the capability of the bienzymatic PANI-PAAMPSA biosensor for gluconic acid measurements and thus for the evaluation of Botrytis cinerea infection in grapes." 01/01/2014 - "In winemaking gluconic acid is an important marker for quantitative evaluation of grape infection by Botrytis cinerea. "
4.	Neoplasms (Cancer) 01/01/1986 - "A phase II trial of immunorestoration with zinc gluconate in immunodepressed cancer patients." 06/01/1982 - "[99mTc-gluconate as a useful brain imaging agent--possibility of differential diagnosis of tumor from non-tumor lesion--]." 07/05/1979 - "Saturation behavior of ascites tumor cell chloride exchange in the presence of gluconate." 03/01/2006 - "In a previous report, we reported a significant reduction in tumor incidence in rat colon as a result of dietary sodium gluconate (GNA). " 12/15/2013 - "Receiver -operating characteristics analysis demonstrated a significant discrimination for all metabolites between malignant and nonmalignant tissue with a maximal area under the curve of 0.86 for tricosanoic acid, whereas no correlation was observed between the metabolite levels and the Gleason score or tumor stage except for gluconic acid. "
5.	Acidosis 05/01/2014 - "Clinical signs resolved, and 6 mo after diagnosis, although the dog remained on alkali therapy (i.e., NaHCO3 and K gluconate) and a mild metabolic acidosis persisted, the dog remained otherwise healthy with a good quality of life. " 11/01/2000 - "With Plasmalyte 148, the acidosis was induced by an increase in unmeasured anions, most probably acetate and gluconate. " 05/01/2012 - "A solution containing a high effective SID (sodium bicarbonate) is much more effective in alkalinizing diarrheic calves with strong ion acidosis than a solution with a low effective SID (sodium gluconate). " 01/01/2012 - "Since infusion of sodium bicarbonate as a buffer seems to be safer than other buffer compounds (lactate, gluconate, acetate)that indirectly convert into it within the liver, We hypothesized tight control of metabolic acidosis by infusion of sodium bicarbonate may improve early post-operative renal function in renal transplant recipients. " 11/01/1990 - "Solutions such as saline or Plasmalyte which had higher concentrations of sodium were more effective at correcting dehydration and electrolyte disturbances than those with less sodium (Darrow's, Hartmann's) but only those with bicarbonate precursors (lactate, acetate, gluconate) were effective in correcting metabolic acidosis. "

Related Drugs and Biologics

1.	Sodium
2.	Antimony
3.	Zinc
4.	Potassium
5.	Sodium Bicarbonate (Baking Soda)
6.	Magnesium
7.	Ketoconazole (Nizoral)
8.	Citric Acid (Citrate)
9.	Amphotericin B (Amphotericin)
10.	Minocycline (Cyclops)

Related Therapies and Procedures

1.	Debridement
2.	Drug Therapy (Chemotherapy)
3.	Cystectomy
4.	Intravenous Injections
5.	Gas Lasers