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lauric acid (dodecanoic acid)

Subscribe to New Research on lauric acid

Also Known As:

dodecanoic acid; lauric acid, ammonium salt; lauric acid, barium and cadmium salt (4:1:1); lauric acid, calcium salt; lauric acid, lithium salt; lauric acid, magnesium salt; lauric acid, nickel(2+) salt; lauric acid, potassium salt; lauric acid, sodium salt; potassium laurate; sodium dodecanoate; sodium laurate

Networked: 94 relevant articles (4 outcomes, 10 trials/studies)

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Bio-Agent Context: Research Results

Lipids: 18571
- Fatty Acids: 6864
  - Lauric Acids: 6
    - lauric acid: 94

Experts

1.	Li, Shengnan: 3 articles (12/2013 - 08/2009)
2.	Jin, Lai: 3 articles (12/2013 - 08/2009)
3.	Ikegaki, Ichiro: 3 articles (09/2009 - 02/2008)
4.	Seto, Minoru: 3 articles (09/2009 - 02/2008)
5.	Asano, Toshio: 3 articles (09/2009 - 02/2008)
6.	Hammock, Bruce D: 3 articles (06/2009 - 04/2005)
7.	King, Michael R: 2 articles (10/2015 - 07/2015)
8.	Mitchell, Michael J: 2 articles (10/2015 - 07/2015)
9.	Castellanos, Carlos A: 2 articles (10/2015 - 07/2015)
10.	Banerjee, Rinti: 2 articles (01/2014 - 04/2007)

Related Diseases

1.	Thrombosis (Thrombus) 08/15/1967 - "Lauric acid-induced thrombocytopenia and thrombosis in rabbits." 11/18/2011 - "More pathological signs of lesions, higher grades of pathological thrombosis, increased blood platelet counts, the increase in the TXB2 and TXB2/6-K-PGF(1α) ratio, as well as the decrease of 6-K-PGF(1α) in TAO model group were shown in present experiments; SFI treatment significantly improved the pathological signs of lesions induced by sodium laurate injection, reduced the numbers of thrombus formation, blood platelet counts, the TXB2 and TXB2/6-K-PGF(1α) ratio but increased the 6-K-PGF(1α) compared with TAO model group. " 09/01/2000 - "Rats were anesthetized with sodium pentobarbital, and 100 microg of sodium laurate was injected into the left internal carotid artery on days 1 and 3. The thrombus induction and consequent of ischemic brain damage were examined by histopathological analyses and neurological deficit scoring in a posture reflex test. " 08/01/1989 - "Its effect on obstruction of the peripheral artery was studied in three different models: 1. acute thrombosis induced by electrical-stimulation of the femoral artery in rabbits, 2. occlusion induced by intra-arterial injection of sodium laurate in rats and 3. tail gangrene induced by subcutaneous injections of both ergotamine and epinephrine in rats. "
2.	Hemolysis 05/01/1973 - "Effect of metabolic inhibitors on lauric acid-induced hemolysis." 04/01/1990 - "The results are summarized as follows: (A) not only at 37 degrees, but also at 42 degrees and 47 degrees C lauric acid (12:0) represents the minimum chain length for the biphasic behaviour of protecting against hypotonic hemolysis at a certain lower concentration range and hemolysis promotion at subsequent higher concentrations; (B) with increasing temperatures the protecting as well as the hemolytic effects occur at lower concentrations of the fatty acids; (C) the increase of temperature promotes the extent of hemolysis and reduces the extent of protection against hypotonic hemolysis; (D) Gamma-irradiation of erythrocytes selectively affects the concentration of oleic acid at which maximum protection against hypotonic hemolysis occurs, without altering the minimum concentration for 100% hemolysis." 10/06/1988 - "The results are summarized as follows: (A) the fatty acids examined exhibit a high degree of specificity in their thermotropic behavior; (B) oleic acid protects against hypotonic hemolysis even at the highest concentrations, up to 15 degrees C, when it becomes hemolytic, but only in a limited concentration range; (C) elaidic acid does not affect the osmotic stability of erythrocytes up to 20 degrees C, when it starts protecting: above 30 degrees C, it becomes hemolytic at the highest concentrations; (D) palmitoleic acid is an excellent protecting agent at all temperatures in a certain concentration range, becoming hemolytic at higher concentrations; (E) lauric acid protects up to 30 degrees C and becomes hemolytic only above this temperature; (F) myristic acid exhibits an extremely unusual behavior at 30 and 37 degrees C by having alternating concentration ranges of protecting and hemolytic effects; (G) there is a common critical temperature for hemolysis at 30 degrees C for saturated and trans-unsaturated fatty acids; (H) the initial slope of Arrhenius plots of percent hemolysis at the concentration of maximum protection is negative for cis-unsaturated fatty acids and positive for saturated and trans-unsaturated fatty acids."
3.	Stroke (Strokes) 03/01/2010 - "We demonstrated that chronic treatment of spontaneously hypertensive stroke-prone rats with 12-(3-adamantan-1-yl-ureido) dodecanoic acid, an inhibitor of SEH, improved the increment of inward remodeling induced by common carotid ligation to a level that was comparable with normotensive Wistar Kyoto rats. " 06/01/2009 - "Here we show that 6 weeks of SEH inhibition via 2 mg/day of 12-(3-adamantan-1-yl-ureido) dodecanoic acid (AUDA) in spontaneously hypertensive stroke-prone (SHRSP) rats protects against cerebral ischemia induced by middle cerebral artery occlusion, reducing percent hemispheric infarct and neurodeficit score without decreasing blood pressure. "
4.	Enteritis 04/01/2010 - "The efficacy of target-released butyric acid, medium-chain fatty acids (C(6) to C(12) but mainly lauric acid) and essential oils (thymol, cinnamaldehyde, essential oil of eucalyptus) micro-encapsulated in a poly-sugar matrix to control necrotic enteritis was investigated. "
5.	Infection 01/01/2014 - "Lauric acid in crown daisy root exudate potently regulates root-knot nematode chemotaxis and disrupts Mi-flp-18 expression to block infection." 01/01/2005 - "Its activity was not influenced by the presence of solid particles and did not cease at pH > 6. Lauric acid might be a means for control of clostridial infections in farm animals." 01/01/2001 - "Lauric acid did not inactivate virion infectivity neither interacted with the cell to induce a state refractory to virus infection. " 11/01/2013 - "Four- to six-week-old male specific pathogen-free BALB/c mice were inoculated intranasally with 10(5) 50% tissue culture infective doses (TCID50) of highly pathogenic A/Chicken/Hebei/108/2002 (H5N1) viruses and were then given 1000 IU of lauric acid modified superoxide dismutase (LA-SOD) by intraperitoneal injection, starting 2 days post-infection and continuing for 6 days. " 01/21/2014 - "A strategy was developed to target infections by producing coatings made of non-toxic chemistries lauric acid and oleic acid delivered by core-shell solid lipid nanoparticles that act against bacteria by multiple mechanisms at the nanoscale, including disruption of bacteria leading to DNA release, and reducing the adhesion of dead bacteria to ~1%. "

Related Drugs and Biologics

1.	Fatty Acids (Saturated Fatty Acids)
2.	Oleic Acid (Oleate)
3.	Troleandomycin (TAO)
4.	Butyric Acid (Butanoic Acid)
5.	Thymol
6.	Prostaglandins F (PGF)
7.	Volatile Oils (Essential Oils)
8.	cinnamic aldehyde (cinnamaldehyde)
9.	lauric acid (dodecanoic acid)
10.	monolaurin

Related Therapies and Procedures

1.	Ligation
2.	Heterologous Transplantation (Xenotransplantation)
3.	Intra-Arterial Injections
4.	Quantum Dots (Quantum Dot)
5.	Transplants (Transplant)