dehydroftorafur

metabolite of FTORAFUR; RN given refers to cpd without isomeric designation

Also Known As:

1-(2,3-dihydro-2-furanyl)-5-fluoro-2,4(1H,3H)-pyrimidinedione; dehydroftorafur, (R)-isomer; dehydroftorafur, (S)-isomer

Networked: 1 relevant articles (0 outcomes, 1 trials/studies)

1.	Gastrointestinal Neoplasms (Gastrointestinal Cancer) 01/01/1981 - "Daily 24-hour serum levels of ftorafur (FT), 5-FU, and a major FT metabolite, dehydroftorafur (DFT), were monitored by high-performance liquid chromatography as part of a phase I study designed to evaluate FT as a radiosensitizing 5-FU pro-drug in patients with advanced gastrointestinal cancers. "