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imidazole

RN given refers to parent cpd

Also Known As:

Al-imidazole; Cu-imidazole; imidazole acetate; imidazole citrate; imidazole conjugate monoacid; imidazole monohydrochloride; imidazole monophosphonate; imidazole sodium; imidazolium chloride

Networked: 804 relevant articles (63 outcomes, 85 trials/studies)

Relationship Network

Bio-Agent Context: Research Results

Heterocyclic Compounds: 60
- 1-Ring Heterocyclic Compounds
  - Azoles: 413
    - Imidazoles: 107
      - imidazole: 804

Experts

1.	Babizhayev, Mark A: 11 articles (11/2015 - 01/2010)
2.	Dervan, Peter B: 9 articles (11/2015 - 11/2004)
3.	Fukuda, Noboru: 9 articles (07/2015 - 03/2010)
4.	Nagase, Hiroki: 8 articles (07/2015 - 03/2010)
5.	Fujiwara, Kyoko: 6 articles (07/2015 - 11/2013)
6.	Soma, Masayoshi: 6 articles (07/2015 - 11/2013)
7.	Yegorov, Yegor E: 5 articles (01/2015 - 01/2010)
8.	Lown, J William: 5 articles (07/2005 - 05/2002)
9.	Ueno, Takahiro: 4 articles (07/2015 - 01/2014)
10.	Watanabe, Takayoshi: 4 articles (01/2015 - 03/2010)

Related Diseases

1.	Infection 01/01/1985 - "Combined penicillin-5 imidazole treatment, effective in preventing local and regional anaerobic infection, resulted in secondary infection developing in about 56% of cases. " 04/01/1961 - "[An imidazole derivative effective in the treatment of experimental infections by Trypanosoma cruzi. " 10/01/2015 - "This study shows that our two new imidazole-derived compounds have good potential as general treatments for Candida infection and as a means to improve the current treatments with FLC." 07/01/2014 - "A control pyridinyl imidazole compound failed to inhibit either EBOV infection or cytokine induction. " 06/16/2007 - "Treatment of a Candida infection consists of a vaginally applied imidazole compound. "
2.	Dermatomycoses (Dermatophytosis) 10/01/1999 - "This biological characteristic of triazole derivative (-)-40 resulted in excellent therapeutic efficacy on dermatophytosis superior to that of the corresponding imidazole derivative ((-)-41)." 01/01/1989 - "Recently, imidazole derivatives are being successfully used for the dermatomycoses. " 01/01/1986 - "This new imidazole derivative has been successfully administered in several cases of dermatophytosis, yeasts and pityriasis versicolor in the authors' clinic, as well as in many other research centres. " 01/01/2013 - "Sertaconazole is a new, broad spectrum, fungicidal and fungistatic imidazole with added antipruritic and anti-inflammatory activity that would provide greater symptomatic relief and hence would be beneficial in improving the quality of life for the patient with dermatophytoses. " 01/01/2002 - "All these results suggest that the combined deactivators-supplemented medium is more useful for mycological evaluation of therapeutic efficacy of imidazole and allylamine drugs against dermatophytoses in both preclinical and clinical studies."
3.	Candidiasis (Moniliasis) 08/01/1985 - "It is concluded that following the elimination of any known predisposing cause of vaginal candidiasis, the intravaginal application of 500 mg of an imidazole preparation is as effective a treatment as any other regimen. " 07/01/1990 - "The vaginal administration of an imidazole antifungal agent is the mainstay of treatment of vaginal candidiasis. " 01/01/2001 - "Based on five trials, imidazole drugs were more effective than nystatin when treating vaginal candidiasis in pregnancy (odds ratio 0.21, 95% confidence interval 0.16 to 0.29). " 01/01/2000 - "Based on five trials, imidazole drugs were more effective than nystatin when treating vaginal candidiasis in pregnancy (odds ratio 0.21, 95% confidence interval 0.16 to 0.29). " 11/01/2002 - "We have recently described the synthesis and antifungal activity of a series of 1,4-benzothiazine and 1,4-benzoxazine imidazole derivatives that mainly showed in vivo activity against a murine experimental model of candidiasis but that very often lacked in vitro activity. "
4.	Tinea Pedis (Athlete's Foot) 10/01/1987 - "The efficacy of both drugs in the treatment of interdigital tinea pedis is similar, and is considerably lower than that found with topical imidazole preparations where cure rates of over 70% are generally expected." 10/01/2011 - "Sertaconazole, an imidazole antifungal agent, is known to be safe and effective when used twice daily in the treatment of tinea pedis. " 05/01/1986 - "This study investigated the clinical effectiveness and the long-term relapse rate of the topical imidazole, econazole nitrate, in the treatment of tinea pedis. " 12/01/1996 - "The usefulness of bifonazole (Mycospor), a topical imidazole antifungal agent approved 10 years ago, was evaluated for the treatment of tinea pedis. " 10/01/1995 - "Short-term topical therapy of experimental tinea pedis in guinea pigs with lanoconazole, a new imidazole antimycotic agent."
5.	Tinea Versicolor 11/01/2015 - "The objective of this research was to evaluate the efficacy of a new antifungal imidazole, dapaconazole tosylate, in the treatment of Pityriasis versicolor (PV). " 12/15/1988 - "In a clinical study from October 1985 to July 1987, we tested the efficacy of 3 different imidazole compounds in 112 male patients suffering from pityriasis versicolor. " 12/15/1988 - "[Local therapy of pityriasis versicolor with 3 imidazole derivatives--results of a therapeutic study. " 01/01/1986 - "It is a member of the imidazole series and is active in superficial and deep mycotic diseases, in candidosis and pityriasis versicolor. " 01/01/1986 - "This new imidazole derivative has been successfully administered in several cases of dermatophytosis, yeasts and pityriasis versicolor in the authors' clinic, as well as in many other research centres. "

Related Drugs and Biologics

1.	Ketoconazole (Nizoral)
2.	Miconazole (Monistat)
3.	Amphotericin B (Amphotericin)
4.	latoconazole (lanoconazole)
5.	sertaconazole
6.	Nylons (Nylon)
7.	Clotrimazole (Lotrimin)
8.	butoconazole (Femstat)
9.	Dactinomycin (Ac-De)
10.	Vincristine (Oncovin)

Related Therapies and Procedures

1.	Intravaginal Administration
2.	Drug Therapy (Chemotherapy)
3.	Heterologous Transplantation (Xenotransplantation)
4.	Ligation
5.	Biological Therapy